ID   HYPD2_BRADU             Reviewed;         380 AA.
AC   P31904;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   28-FEB-2003, sequence version 2.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Hydrogenase maturation factor HypD2 {ECO:0000250|UniProtKB:P24192};
GN   Name=hypD2; Synonyms=hypD, hypD'; OrderedLocusNames=bll6928;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 34-380.
RC   STRAIN=CB1809;
RX   PubMed=8510650; DOI=10.1007/bf00281623;
RA   van Soom C., Verreth C., Sampaio M.J., Vanderleyden J.;
RT   "Identification of a potential transcriptional regulator of hydrogenase
RT   activity in free-living Bradyrhizobium japonicum strains.";
RL   Mol. Gen. Genet. 239:235-240(1993).
CC   -!- FUNCTION: Involved in the maturation of [NiFe] hydrogenases. Involved
CC       in the biosynthesis of the Fe(CN)(2)CO cofactor.
CC       {ECO:0000250|UniProtKB:P24192}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000250|UniProtKB:P24192};
CC   -!- PATHWAY: Protein modification; [NiFe] hydrogenase maturation.
CC       {ECO:0000250|UniProtKB:P24192}.
CC   -!- SIMILARITY: Belongs to the HypD family. {ECO:0000305}.
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DR   EMBL; BA000040; BAC52193.1; -; Genomic_DNA.
DR   EMBL; Z17373; CAA78988.1; -; Genomic_DNA.
DR   PIR; S35229; S35229.
DR   RefSeq; NP_773568.1; NC_004463.1.
DR   RefSeq; WP_011089666.1; NZ_CP011360.1.
DR   AlphaFoldDB; P31904; -.
DR   SMR; P31904; -.
DR   STRING; 224911.27355209; -.
DR   EnsemblBacteria; BAC52193; BAC52193; BAC52193.
DR   GeneID; 64026684; -.
DR   KEGG; bja:bll6928; -.
DR   PATRIC; fig|224911.44.peg.6962; -.
DR   eggNOG; COG0409; Bacteria.
DR   HOGENOM; CLU_048562_1_0_5; -.
DR   InParanoid; P31904; -.
DR   OMA; PWALMEV; -.
DR   PhylomeDB; P31904; -.
DR   UniPathway; UPA00335; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR   GO; GO:0070025; F:carbon monoxide binding; IBA:GO_Central.
DR   GO; GO:0005506; F:iron ion binding; IBA:GO_Central.
DR   GO; GO:0051604; P:protein maturation; IBA:GO_Central.
DR   Gene3D; 3.40.50.11750; -; 2.
DR   Gene3D; 6.10.20.100; -; 1.
DR   InterPro; IPR002780; Hyd_form_HypD.
DR   InterPro; IPR042243; HypD_1.
DR   InterPro; IPR042244; HypD_2_sf.
DR   PANTHER; PTHR30149; PTHR30149; 1.
DR   Pfam; PF01924; HypD; 1.
DR   PIRSF; PIRSF005622; Hydrgn_mat_hypD; 1.
DR   TIGRFAMs; TIGR00075; hypD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..380
FT                   /note="Hydrogenase maturation factor HypD2"
FT                   /id="PRO_0000201450"
FT   BINDING         36
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   BINDING         64
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   BINDING         67
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   CONFLICT        54
FT                   /note="K -> A (in Ref. 2; CAA78988)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        82
FT                   /note="E -> M (in Ref. 2; CAA78988)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        261
FT                   /note="S -> T (in Ref. 2; CAA78988)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   380 AA;  42477 MW;  2C416E80BE8C2939 CRC64;
     MKYADEFRDK EIALGLAKAI RAEADPRKPY RFMEFCGGHT HAISRYGLED MLPKNVRMIH
     GPGCPVCVLP AGRIDMAIRL AERPDIILCV YGDLMRVPGS QGASLLKAKA RGADIRMVYS
     TIDAIRIAED NPGREVVFFA IGFETTTPPT AVMIRLAGKK QLENFSVFCN HVLTPPAMQN
     ILESPDIRNI GRVEIDGFVG PAHVSTIIGT APYEFFAEEF GKPVVIAGFE PLDMMQAILM
     LVRQVNEHRH EVENQYSRAV SRDGNLRAKE EVSDIFELRD QFEWRGLGQV PYSGLKLKRA
     YAKYDAEVRF DMNELRVDDN PACECGAILR GVKKPVDCKL FGTVCTPETP MGSCMVSSEG
     ACAAHWTYGR FRDHQQRRAS