ID   HYPD_RHILV              Reviewed;         385 AA.
AC   P40598;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Hydrogenase maturation factor HypD {ECO:0000250|UniProtKB:P24192};
GN   Name=hypD;
OS   Rhizobium leguminosarum bv. viciae.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=387;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=128c53;
RX   PubMed=8326860; DOI=10.1111/j.1365-2958.1993.tb01591.x;
RA   Rey L., Murillo J., Hernando Y., Hidalgo E., Cabrera E., Imperial J.,
RA   Ruiz-Argueso T.;
RT   "Molecular analysis of a microaerobically induced operon required for
RT   hydrogenase synthesis in Rhizobium leguminosarum biovar viciae.";
RL   Mol. Microbiol. 8:471-481(1993).
CC   -!- FUNCTION: Involved in the maturation of [NiFe] hydrogenases. Involved
CC       in the biosynthesis of the Fe(CN)(2)CO cofactor.
CC       {ECO:0000250|UniProtKB:P24192}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000250|UniProtKB:P24192};
CC   -!- PATHWAY: Protein modification; [NiFe] hydrogenase maturation.
CC       {ECO:0000250|UniProtKB:P24192}.
CC   -!- SIMILARITY: Belongs to the HypD family. {ECO:0000305}.
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DR   EMBL; X52974; CAA37163.1; -; Genomic_DNA.
DR   PIR; S32877; S32877.
DR   AlphaFoldDB; P40598; -.
DR   SMR; P40598; -.
DR   UniPathway; UPA00335; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.11740; -; 2.
DR   Gene3D; 6.10.20.100; -; 1.
DR   InterPro; IPR002780; Hyd_form_HypD.
DR   InterPro; IPR042243; HypD_1.
DR   InterPro; IPR042244; HypD_2_sf.
DR   PANTHER; PTHR30149; PTHR30149; 1.
DR   Pfam; PF01924; HypD; 1.
DR   PIRSF; PIRSF005622; Hydrgn_mat_hypD; 1.
DR   TIGRFAMs; TIGR00075; hypD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding.
FT   CHAIN           1..385
FT                   /note="Hydrogenase maturation factor HypD"
FT                   /id="PRO_0000201452"
FT   BINDING         36
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   BINDING         64
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   BINDING         67
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
SQ   SEQUENCE   385 AA;  42028 MW;  0B15216C15665B12 CRC64;
     MKYIDEYRDG SLAKDVARQI TALADPARSY HFMEFCGGHT HAISRYGLED LLPANVRMIH
     GPGCPVCVLP IGRIDAAIAL AMRPEITLCT YGDLMRVPGS NGSSLLKAKA AGADIRMVYS
     TLDALRIADA EPDREVVFFA IGFETTTPTT ALALKAAIAR GLGNFSIFCN HVLTPAPIQN
     ILESPDVRKL GTIKIDGFIG PAHVSTVIGT EPYEFFAEEF RKPVVVAGFE PLDVIQAILM
     LVRQVNDGRH EVENQYIRAV TALGNEKAQA EVANFFELRE SFEWRGLGEV PYGALRLRPQ
     YAAYDAEKRF SMVTPAAKDN PACECGAILR GVKKPADCKL FGTVCTPDTP MGSCMVSPEG
     ACAAHWAYGR FREKVRQVDA RRAVA