ID   I1_MONPZ                Reviewed;         312 AA.
AC   Q8V518;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   23-FEB-2022, entry version 47.
DE   RecName: Full=Telomere-binding protein I1;
DE   AltName: Full=36 kDa late protein I1;
GN   ORFNames=I1L;
OS   Monkeypox virus (strain Zaire-96-I-16) (MPX).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=619591;
OH   NCBI_TaxID=45479; Cynomys gunnisoni (Gunnison's prairie dog).
OH   NCBI_TaxID=99825; Cynomys leucurus (White-tailed prairie dog).
OH   NCBI_TaxID=45480; Cynomys ludovicianus (Black-tailed prairie dog).
OH   NCBI_TaxID=99826; Cynomys mexicanus (Mexican prairie dog).
OH   NCBI_TaxID=99827; Cynomys parvidens (Utah prairie dog).
OH   NCBI_TaxID=30650; Gliridae (dormice).
OH   NCBI_TaxID=226685; Heliosciurus ruwenzorii (Ruwenzori sun squirrel).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zaire-96-I-16;
RX   PubMed=11734207; DOI=10.1016/s0014-5793(01)03144-1;
RA   Shchelkunov S.N., Totmenin A.V., Babkin I.V., Safronov P.F.,
RA   Ryazankina O.I., Petrov N.A., Gutorov V.V., Uvarova E.A., Mikheev M.V.,
RA   Sisler J.R., Esposito J.J., Jahrling P.B., Moss B., Sandakhchiev L.S.;
RT   "Human monkeypox and smallpox viruses: genomic comparison.";
RL   FEBS Lett. 509:66-70(2001).
CC   -!- FUNCTION: Late DNA-binding protein which binds to the hairpin form of
CC       the viral telomeric sequence. Required for the production of mature
CC       virions (MV) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Present in the virus
CC       core. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF380138; AAL40520.1; -; Genomic_DNA.
DR   RefSeq; NP_536489.1; NC_003310.1.
DR   SMR; Q8V518; -.
DR   GeneID; 929042; -.
DR   KEGG; vg:929042; -.
DR   Proteomes; UP000101269; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004969; Poxvirus_I1.
DR   Pfam; PF03289; Pox_I1; 1.
DR   PIRSF; PIRSF015625; VAC_I1L; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Late protein; Virion.
FT   CHAIN           1..312
FT                   /note="Telomere-binding protein I1"
FT                   /id="PRO_0000099563"
SQ   SEQUENCE   312 AA;  35870 MW;  2B51E66D788C2391 CRC64;
     MAEFEDQLVF NSISARALKA YFTAKINEMV DELVTRKCPQ KKKSQAKKPE VRIPVDLVKS
     SFVKKFGLCN YGGILISLIN SLVENNFFTK NGKLDDTGKK ELVLTDVEKR ILNTIDKSSP
     LYIDISDVKV LAARLKRSAT QFNFNGHTYH LENDKIEDLI NQLVKDESIQ LDEKSSIKDS
     MYVIPDELID VLKTRLFRSP QVKDNIISRT RLYDYFTRVT KRDESSIYVI LKDPRIASIL
     SLETVKMGAF MYTKHSMLTN AISSRVDRYS KKFQESFYED IAEFVKENER VNVSRVVECL
     TVPNITISSN TE