ID   I1_VACCP                Reviewed;         312 AA.
AC   Q9QBG0;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   23-FEB-2022, entry version 42.
DE   RecName: Full=Telomere-binding protein I1;
OS   Vaccinia virus (strain L-IVP) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=31531;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8237112; DOI=10.1016/0168-1702(93)90067-w;
RA   Ryazankina O.I., Muravlev A.I., Gutorov V.V., Mikrjukov N.N.,
RA   Cheshenko I.O., Shchelkunov S.N.;
RT   "Comparative analysis of the conserved region of the orthopoxvirus genome
RT   encoding the 36K and 12K proteins.";
RL   Virus Res. 29:281-303(1993).
CC   -!- FUNCTION: Late DNA-binding protein which binds to the hairpin form of
CC       the viral telomeric sequence. Required for the production of mature
CC       virions (MV) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Present in the virus
CC       core. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- MISCELLANEOUS: Each virion contains approximately 670 molecules of I1.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I1 family. {ECO:0000305}.
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DR   EMBL; X61165; CAB57396.1; -; Genomic_DNA.
DR   EMBL; X61166; CAB57396.1; JOINED; Genomic_DNA.
DR   PIR; PN0121; PN0121.
DR   SMR; Q9QBG0; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004969; Poxvirus_I1.
DR   Pfam; PF03289; Pox_I1; 1.
DR   PIRSF; PIRSF015625; VAC_I1L; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Late protein; Virion.
FT   CHAIN           1..312
FT                   /note="Telomere-binding protein I1"
FT                   /id="PRO_0000099559"
SQ   SEQUENCE   312 AA;  35901 MW;  86AAC403456A8CA3 CRC64;
     MAEFEDQLVF NSISARALKA YFTAKINEMV DELVTRKCPQ KKKSQAKKPE VRIPVDLVKS
     SFVKKFGLCN YGGILISLIN SLVENNFFTK DGKLDDTGKK ELVLTDVEKR ILNAIDKSSP
     LYIDISDVKV LAARLKRSAT QFNFNGHTYH LENDKIEDLI NQLVKDESIQ LDEKSSIKDS
     MYVIPDELID VLKTRLFRSP QVKDNIISRT RLYDYFTRVT KRDESSIYVI LKDPRIASIL
     SLETVKMGAF MYTKHSMLTN AISSRVDRYS KKFQESFYED ITEFVKENER VNVSRVVEYL
     TVPNITISSN AE