ID   I1_VACCT                Reviewed;         312 AA.
AC   Q77TL8;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Telomere-binding protein I1;
GN   ORFNames=TI1L;
OS   Vaccinia virus (strain Tian Tan) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10253;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jin Q., Hou Y.D., Cheng N.H., Yao E.M., Cheng S.X., Yang X.K., Jing D.Y.,
RA   Yu W.H., Yuan J.S., Ma X.J.;
RT   "Complete genomic sequence of vaccinia virus (Tian Tan strain).";
RL   Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Late DNA-binding protein which binds to the hairpin form of
CC       the viral telomeric sequence. Required for the production of mature
CC       virions (MV) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Present in the virus
CC       core. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- MISCELLANEOUS: Each virion contains approximately 670 molecules of I1.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I1 family. {ECO:0000305}.
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DR   EMBL; AF095689; AAF33929.1; -; Genomic_DNA.
DR   SMR; Q77TL8; -.
DR   Proteomes; UP000163220; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004969; Poxvirus_I1.
DR   Pfam; PF03289; Pox_I1; 1.
DR   PIRSF; PIRSF015625; VAC_I1L; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Late protein; Virion.
FT   CHAIN           1..312
FT                   /note="Telomere-binding protein I1"
FT                   /id="PRO_0000099560"
SQ   SEQUENCE   312 AA;  35841 MW;  A7C17EA3F466679F CRC64;
     MAEFEDQLVF NSISARALKA YFTAKINEMV DELVTRKCPQ KKKSQAKKPE VRIPVDLVKS
     SFVKKFGLCN YGGILISLIN SLVENNFFTK DGKLDDTGKK ELVLTDVEKR ILNTIDKSSP
     LYIDISDVKV LAARLKRSAT QFNFNGHTYH LENDKIEDLI NQLVKDESIQ LDEKSSIKDS
     MYVIPDELID VLKTRLFRSP QVKDNIISRT RLYDYFTRVT KRDESSIYVI LKDPRIASIL
     SLETVKMGAF MYTKHSMLTN AISSRVDRYS KKFQESFYED IAEFVKENER VNVSRVVECL
     TVPNITISSN AE