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I2B7_CONPO
ID   I2B7_CONPO              Reviewed;          74 AA.
AC   C7DQX9;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Conotoxin Vi11.7 {ECO:0000303|PubMed:19595726};
DE   Flags: Precursor;
OS   Conus planorbis (Planorbis cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Strategoconus.
OX   NCBI_TaxID=97183;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=19595726; DOI=10.1016/j.peptides.2009.06.036;
RA   Liu Z., Xu N., Hu J., Zhao C., Yu Z., Dai Q.;
RT   "Identification of novel I-superfamily conopeptides from several clades of
RT   Conus species found in the South China Sea.";
RL   Peptides 30:1782-1787(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:19595726}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:19595726}.
CC   -!- DOMAIN: The cysteine framework is XI (C-C-CC-CC-C-C). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the conotoxin I2 superfamily. {ECO:0000305}.
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DR   EMBL; GQ184579; ACU30736.1; -; mRNA.
DR   AlphaFoldDB; C7DQX9; -.
DR   SMR; C7DQX9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013141; Conotoxin-I_CS.
DR   InterPro; IPR020242; Conotoxin_I2-superfamily.
DR   Pfam; PF17557; Conotoxin_I2; 1.
DR   PROSITE; PS60019; I_CONOTOXIN; 1.
PE   3: Inferred from homology;
KW   Cleavage on pair of basic residues; Disulfide bond; Secreted; Signal;
KW   Toxin.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250"
FT   PEPTIDE         27..59
FT                   /note="Conotoxin Vi11.7"
FT                   /id="PRO_0000392047"
FT   PROPEP          62..74
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000392048"
FT   DISULFID        28..42
FT                   /evidence="ECO:0000250|UniProtKB:Q7Z094"
FT   DISULFID        35..47
FT                   /evidence="ECO:0000250|UniProtKB:Q7Z094"
FT   DISULFID        41..51
FT                   /evidence="ECO:0000250|UniProtKB:Q7Z094"
FT   DISULFID        46..55
FT                   /evidence="ECO:0000250|UniProtKB:Q7Z094"
SQ   SEQUENCE   74 AA;  8364 MW;  F38E921EAA94B6F9 CRC64;
     MMFRLTSVGC FLLVIVLLNV AVLTNASCRN EGAMCSFGFQ CCKKECCMSH CTDFCRNPDK
     RAHGHGLLRF WGQR
 
 
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