ID   I2BLA_XENLA             Reviewed;         690 AA.
AC   Q66IY8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Interferon regulatory factor 2-binding protein-like A;
DE   AltName: Full=Enhanced at puberty protein 1 homolog A;
GN   Name=irf2bpl-a; Synonyms=eap1-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRF2BP family. {ECO:0000305}.
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DR   EMBL; BC081137; AAH81137.1; -; mRNA.
DR   RefSeq; NP_001087721.1; NM_001094252.1.
DR   AlphaFoldDB; Q66IY8; -.
DR   SMR; Q66IY8; -.
DR   DNASU; 447545; -.
DR   GeneID; 447545; -.
DR   KEGG; xla:447545; -.
DR   CTD; 447545; -.
DR   OMA; WASKPKM; -.
DR   OrthoDB; 1156771at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 447545; Expressed in blastula and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.1580; -; 1.
DR   InterPro; IPR044882; I2BP1/2_C3HC4-RING_sf.
DR   InterPro; IPR022750; Interferon_reg_fac2-bd1_2_Znf.
DR   Pfam; PF11261; IRF-2BP1_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..690
FT                   /note="Interferon regulatory factor 2-binding protein-like
FT                   A"
FT                   /id="PRO_0000328732"
FT   ZN_FING         609..656
FT                   /note="RING-type; degenerate"
FT   REGION          59..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          231..263
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        63..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..229
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..251
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        479..505
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        507..523
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..573
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   690 AA;  72642 MW;  4FAAD1E7A9FC17AC CRC64;
     MSAAQVSSSR RQSCYLCDLP RMPWAMIWDF TEPVCRGCVN YEGADRIEFV IDTARQLKRS
     HSFQDGRSPG PQGPGSGASN KQHPAVQAAL TAKDTAQLNH LDGATKAAAA SGLERYGLTT
     DRGRFEYTLA ARLPNGLNGF PKPGEDGPPE LNRQSPNSRG RTGHGLIPQL VPGQLSVPPN
     LIPQTLLNGP PPGTPGGAPH VLGRGPASSS GLGVPPTASS SGDPKRPGSV SSTDQERELK
     EKQRNSEALS ELTESLRNRA EEWAGKPKAV RDTLLTLTAS TPFDVRFKKD HNLLGRVFAF
     DAASKPGLLD YELKLFVEYP SGSLNVFSSA SGVAKQMYQD CMKDFGRGLS SGFKYLEYEK
     KHGSGDWRLL GDLLPESVRF FKEMVGADML PQPYLDPGCP MLPSALVNLP RALAAAAAAS
     SSAGSSGQAR SGVRKRKASP EPDSADGQMW LTGQPDGIKQ LSMAPAGGTP SSSSAAYGVP
     SAPPPPLGPG HPQRTTPPES APPNGPSPMA ALQSVTDTLG TAHSPKDGQA GGLPPVHSTT
     SSARRNSSSP VSPASVTGQR RLNSRNGAGS AELSLQVAPT GGAPHPGMDQ VHPQNIPDSP
     MANSGPLCCT ICHERLEDTH FVQCPSVPSH KFCFPCSRDS IKAQGATGEV YCPSGEKCPL
     VGSNVPWAFM QGEIATILAG DVKVKKERDP