ID   I2BLB_XENLA             Reviewed;         690 AA.
AC   Q6PCG7;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Interferon regulatory factor 2-binding protein-like B;
DE   AltName: Full=Enhanced at puberty protein 1 homolog B;
GN   Name=irf2bpl-b; Synonyms=eap1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRF2BP family. {ECO:0000305}.
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DR   EMBL; BC059332; AAH59332.1; -; mRNA.
DR   RefSeq; NP_001080026.1; NM_001086557.1.
DR   AlphaFoldDB; Q6PCG7; -.
DR   SMR; Q6PCG7; -.
DR   DNASU; 379718; -.
DR   GeneID; 379718; -.
DR   KEGG; xla:379718; -.
DR   CTD; 379718; -.
DR   OrthoDB; 1156771at2759; -.
DR   Proteomes; UP000186698; Chromosome 8S.
DR   Bgee; 379718; Expressed in lung and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.1580; -; 1.
DR   InterPro; IPR044882; I2BP1/2_C3HC4-RING_sf.
DR   InterPro; IPR022750; Interferon_reg_fac2-bd1_2_Znf.
DR   Pfam; PF11261; IRF-2BP1_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..690
FT                   /note="Interferon regulatory factor 2-binding protein-like
FT                   B"
FT                   /id="PRO_0000328733"
FT   ZN_FING         609..656
FT                   /note="RING-type; degenerate"
FT   REGION          59..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          136..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          418..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          231..259
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        63..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..229
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..263
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..432
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        447..478
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        479..505
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        507..525
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        533..564
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   690 AA;  72849 MW;  4EB97AE0088E299B CRC64;
     MSAAQVSSSR RQSCYLCDLP RMPWAMIWDF TEPVCRGCVN YEGADRIEFV IDTARQLKRS
     HSFQDGRSPG PQGPGSGASN KQHPAVQAAL TAKDTAQLNH LDGATKASAA SGLERYGLAT
     ERGRFEYSLA ARLPNGLNGF PKPGEDGPPE LNRQSPNSRG RSGHGLIPQL VPGQLSVPPN
     LLPQTLLNGP PSGNPTGAPH VLGRGPANSS GLGVPPTASS SGDPKRPGSV SSTDQERELK
     EKQRNSEALS ELTESLRNRT EEWVGKPKAV RDALLTLTAS APFDVRFKKD HNLLGRVFAF
     DAASKPGLLD YELKLFVEYP SGSLNIFSSA SGVAKQMYQD CMKDFGRGLS SGFKYLEYEK
     KHGSGDWRLL GDLLPESVRF FKEMVGADML PQPYLDPGCP MLPSALVNLP RALAAAAASS
     SAGSSGQTRS GVRKRKASPE PDSADGQMWI TGQSDGIKQL SMAPAGVTPS SSSSAAYGVP
     SAPPPPLGPG HPQRTTPPES APPNGPSPMA ALQSVTDTLG NAHSPKEGQT GGIPPVHSTT
     SSARRNSSSP VSPASVTGQR RLNSRNGAGS VELSLQVAPA GGAPHLGMDQ VHPQNIPDSP
     MANSGPLCCT ICHERLEDTH FVQCPSVPSH KFCFPCSRDS IKAQGATGEV YCPSGEKCPL
     VGSNVPWAFM QGEIATILAG DVKVKKERDP