ID   APA_MYCAV               Reviewed;         381 AA.
AC   Q48919;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Alanine and proline-rich secreted protein Apa;
DE   AltName: Full=45/47 kDa antigen;
DE   AltName: Full=FAP-A;
DE   AltName: Full=Fibronectin attachment protein;
DE   Flags: Precursor;
GN   Name=apa;
OS   Mycobacterium avium.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=1764;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=101;
RX   PubMed=8858587; DOI=10.1046/j.1365-2958.1996.6381353.x;
RA   Schorey J.S., Holsti M.A., Ratliff T.L., Allen P.M., Brown E.J.;
RT   "Characterization of the fibronectin-attachment protein of Mycobacterium
RT   avium reveals a fibronectin-binding motif conserved among mycobacteria.";
RL   Mol. Microbiol. 21:321-329(1996).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the Apa family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U53585; AAB50543.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q48919; -.
DR   SMR; Q48919; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:InterPro.
DR   InterPro; IPR010801; FAP.
DR   Pfam; PF07174; FAP; 1.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..381
FT                   /note="Alanine and proline-rich secreted protein Apa"
FT                   /id="PRO_0000020742"
FT   REGION          35..137
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          300..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..134
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..370
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   381 AA;  38211 MW;  0DACB9A22AA11D2B CRC64;
     MDQVEATSTR RKGLWTTLAI TTVSGASAVV IALPETSHAD PEVPTPVPPS TATTPHPRRR
     RIPGQPADNA QAGAPAPAPN GQQRPPRRRR MIPTRAPPPA GAPPNGAPPA APNGAPPPPV
     DPNAPPPPPA DPNAGRIPNS YVLPAGWVES DASHLDYGSA LLSKVTGPPP MPDQPPPVAN
     DTRIVMGRVD QKLYASAEAN NAKAAVGLGS DMGEFFMPYP GTRINQDSTP LNGANGSTGS
     ASYYEVKFSD ASKPNGQIWT GVIGSANAGN RQRWFVVWLG TSNDPVDKVA AKALAESIQA
     WTPPPAPPAA PGGPGAPAPG APGAPAPGAP AAPGVTAPAA PAPAAPGAPA APGAPAPEPG
     QAPAVEVSPT PTPTPQQTLS A