ID   I5L_FOWPN               Reviewed;          81 AA.
AC   P18521;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   12-AUG-2020, entry version 59.
DE   RecName: Full=Protein I5 homolog;
GN   OrderedLocusNames=FPV085; ORFNames=FPI5L;
OS   Fowlpox virus (strain NVSL) (FPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Avipoxvirus.
OX   NCBI_TaxID=928301;
OH   NCBI_TaxID=7742; Vertebrata.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FP-9 / Isolate HP-444;
RX   PubMed=2838574; DOI=10.1099/0022-1317-69-6-1275;
RA   Binns M.M., Tomley F.M., Campbell J., Boursnell M.E.G.;
RT   "Comparison of a conserved region in fowlpox virus and vaccinia virus
RT   genomes and the translocation of the fowlpox virus thymidine kinase gene.";
RL   J. Gen. Virol. 69:1275-1283(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FP-9 / Isolate HP-440;
RX   PubMed=1326827; DOI=10.1016/0168-1702(92)90004-s;
RA   Binns M.M., Boursnell M.E.G., Skinner M.A.;
RT   "Gene translocations in poxviruses: the fowlpox virus thymidine kinase gene
RT   is flanked by 15 bp direct repeats and occupies the locus which in vaccinia
RT   virus is occupied by the ribonucleotide reductase large subunit gene.";
RL   Virus Res. 24:161-172(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10729156; DOI=10.1128/jvi.74.8.3815-3831.2000;
RA   Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
RT   "The genome of fowlpox virus.";
RL   J. Virol. 74:3815-3831(2000).
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Multi-pass
CC       membrane protein. Note=Probably localizes to the membrane of mature
CC       virions (MV). {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the Chordopoxvirinae I5 family. {ECO:0000305}.
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DR   EMBL; D00320; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; D00321; BAA00232.1; -; Genomic_DNA.
DR   EMBL; AJ223385; CAA11296.1; -; Genomic_DNA.
DR   EMBL; AF198100; AAF44429.1; -; Genomic_DNA.
DR   PIR; JS0228; WMVZ44.
DR   RefSeq; NP_039048.1; NC_002188.1.
DR   GeneID; 1486633; -.
DR   KEGG; vg:1486633; -.
DR   Proteomes; UP000008597; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006803; Poxvirus_I5.
DR   Pfam; PF04713; Pox_I5; 1.
DR   PIRSF; PIRSF003768; VAC_I5L; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Virion.
FT   CHAIN           1..81
FT                   /note="Protein I5 homolog"
FT                   /id="PRO_0000099730"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   81 AA;  9123 MW;  1E9B4A571CC97B74 CRC64;
     MEIARETLIT IGLTILVVLL IITGFSLVLR LIPGVYSSVS RSSFTAGRIL RFMEIFSTIM
     FIPGIIILYA AYIRKIKMKN N