ID   I6_VACCC                Reviewed;         382 AA.
AC   P68463; P12925;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   23-FEB-2022, entry version 39.
DE   RecName: Full=Telomere-binding protein I6;
GN   ORFNames=I6L;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Binds to the hairpin form of the viral telomeric sequence.
CC       Might direct genome encapsidation into the virus particle (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Present in the virus
CC       core. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I6 family. {ECO:0000305}.
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DR   EMBL; M35027; AAA48062.1; -; Genomic_DNA.
DR   PIR; F29889; WZVZI6.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   InterPro; IPR007674; Poxvirus_36kDa_major_membrane.
DR   InterPro; IPR022219; Poxvirus_I6_C.
DR   Pfam; PF12562; DUF3746; 1.
DR   Pfam; PF04595; Pox_I6; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Virion.
FT   CHAIN           1..382
FT                   /note="Telomere-binding protein I6"
FT                   /id="PRO_0000099578"
SQ   SEQUENCE   382 AA;  43454 MW;  4D0F72666DEE1307 CRC64;
     MNNFVKQVAS KSLKPTKKLS PSDEVISLNE CIISFNLDNF YYCNDGLFTK PINTPEDVLK
     SLLIMESFAY EKMIIKGLIK ILISRAYIND IYFTPFGWLT GVDDDPETHV VIKIIFNSSL
     ISIKSQVIEY LKPYNVNNLS VLTTEKELSI NTFNVPDSIP MSIISFFPFD TDFILVILFF
     GVYNDSYCGI SYISPKERLP YIIEILKPLV SEINMLSDEI GRTSSIRIFN STSVKKFPTN
     TLTSICEIVY SFDESSFPTP KTFTPLNASP YIPKKIVSLL DLPSNVEIKA ISRGGVDFIT
     HINNKRLNTI LVIAKDNFLK NSTFSGTFIK ENIIWKGIYT YRIIKSSFPV PTIKSVTNKK
     KICKKHCFVN SQYTTRTLSH IL