ID   IAA2_STROI              Reviewed;          75 AA.
AC   P20596;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Alpha-amylase inhibitor Paim-2;
DE   AltName: Full=Pig pancreatic alpha-amylase inhibitor of microbes II;
DE            Short=Paim II;
OS   Streptomyces olivaceoviridis (Streptomyces corchorusii).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1921;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=2783847; DOI=10.1016/s0006-291x(89)80079-8;
RA   Akashi S., Hirayama K., Murai A., Arai M., Murao S.;
RT   "Determination of the primary structure of Paim II, an alpha-amylase
RT   inhibitor from Streptomyces coruchorushii, by high-performance tandem mass
RT   spectrometry.";
RL   Biochem. Biophys. Res. Commun. 158:514-519(1989).
CC   -!- FUNCTION: Inhibits mammalian alpha-amylases specifically but has no
CC       action on plant and microbial alpha-amylases.
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DR   PIR; A31298; A31298.
DR   AlphaFoldDB; P20596; -.
DR   SMR; P20596; -.
DR   GO; GO:0015066; F:alpha-amylase inhibitor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.20; -; 1.
DR   InterPro; IPR000833; A-amylase_inhib.
DR   InterPro; IPR036379; A-amylase_inhib_sf.
DR   Pfam; PF01356; A_amylase_inhib; 1.
DR   PIRSF; PIRSF001658; Amylase_inhib; 1.
DR   SMART; SM00783; A_amylase_inhib; 1.
DR   SUPFAM; SSF49498; SSF49498; 1.
PE   1: Evidence at protein level;
KW   Alpha-amylase inhibitor; Direct protein sequencing; Disulfide bond.
FT   CHAIN           1..75
FT                   /note="Alpha-amylase inhibitor Paim-2"
FT                   /id="PRO_0000203592"
FT   DISULFID        10..26
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..72
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   75 AA;  7626 MW;  0AE6A3548D5FE1E4 CRC64;
     SDASEPAPAC VVMYESWRYT TAANNCADTV SVSVAYQDGA TGPCATLPPG AVTTVGEGYL
     GEHGHPDHLA LCPSS