ID   IAA33_ARATH             Reviewed;         171 AA.
AC   Q9FKM7; Q2VW96;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Auxin-responsive protein IAA33;
DE   AltName: Full=Indoleacetic acid-induced protein 33;
GN   Name=IAA33; OrderedLocusNames=At5g57420; ORFNames=MUA2.1;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Yamada K., Chang C.H., Onodera C.S., Yu G., Theologis A.;
RT   "Arabidopsis open reading frame (ORF) clones.";
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY, NOMENCLATURE, AND FUNCTION.
RX   PubMed=12036262; DOI=10.1023/a:1015255030047;
RA   Liscum E., Reed J.W.;
RT   "Genetics of Aux/IAA and ARF action in plant growth and development.";
RL   Plant Mol. Biol. 49:387-400(2002).
CC   -!- FUNCTION: Aux/IAA proteins are short-lived transcriptional factors that
CC       function as repressors of early auxin response genes at low auxin
CC       concentrations. Repression is thought to result from the interaction
CC       with auxin response factors (ARFs), proteins that bind to the auxin-
CC       responsive promoter element (AuxRE). Formation of heterodimers with ARF
CC       proteins may alter their ability to modulate early auxin response genes
CC       expression. {ECO:0000269|PubMed:12036262}.
CC   -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q9FKM7; Q93YR9: ARF16; NbExp=7; IntAct=EBI-3946739, EBI-3947588;
CC       Q9FKM7; Q9C5W9: ARF18; NbExp=6; IntAct=EBI-3946739, EBI-3946783;
CC       Q9FKM7; Q8RYC8: ARF19; NbExp=4; IntAct=EBI-3946739, EBI-529887;
CC       Q9FKM7; Q94JM3: ARF2; NbExp=3; IntAct=EBI-3946739, EBI-1799262;
CC       Q9FKM7; A0A2H1ZEC0: ARF20; NbExp=3; IntAct=EBI-3946739, EBI-25527665;
CC       Q9FKM7; Q9LS00: HHO1; NbExp=3; IntAct=EBI-3946739, EBI-15203988;
CC       Q9FKM7; Q38828: IAA10; NbExp=6; IntAct=EBI-3946739, EBI-3946434;
CC       Q9FKM7; Q38831: IAA13; NbExp=6; IntAct=EBI-3946739, EBI-1554143;
CC       Q9FKM7; O24407: IAA16; NbExp=3; IntAct=EBI-3946739, EBI-632231;
CC       Q9FKM7; P93830: IAA17; NbExp=5; IntAct=EBI-3946739, EBI-632243;
CC       Q9FKM7; O24409: IAA19; NbExp=3; IntAct=EBI-3946739, EBI-632257;
CC       Q9FKM7; O24410: IAA20; NbExp=6; IntAct=EBI-3946739, EBI-632272;
CC       Q9FKM7; Q8LAL2: IAA26; NbExp=5; IntAct=EBI-3946739, EBI-3947418;
CC       Q9FKM7; Q9ZSY8: IAA27; NbExp=6; IntAct=EBI-3946739, EBI-3946677;
CC       Q9FKM7; Q9XFM0: IAA28; NbExp=7; IntAct=EBI-3946739, EBI-3133404;
CC       Q9FKM7; Q38822: IAA3; NbExp=3; IntAct=EBI-3946739, EBI-307174;
CC       Q9FKM7; Q8H174: IAA31; NbExp=6; IntAct=EBI-3946739, EBI-3946408;
CC       Q9FKM7; Q8RYC6: IAA32; NbExp=3; IntAct=EBI-3946739, EBI-3946448;
CC       Q9FKM7; Q9C5X0: IAA34; NbExp=9; IntAct=EBI-3946739, EBI-3946459;
CC       Q9FKM7; P33077: IAA4; NbExp=3; IntAct=EBI-3946739, EBI-632187;
CC       Q9FKM7; Q38824: IAA6; NbExp=5; IntAct=EBI-3946739, EBI-1554124;
CC       Q9FKM7; Q9C9L2: TCP15; NbExp=3; IntAct=EBI-3946739, EBI-4426144;
CC       Q9FKM7; Q9MAH8: TCP3; NbExp=3; IntAct=EBI-3946739, EBI-25522447;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- INDUCTION: By auxin. {ECO:0000250}.
CC   -!- DOMAIN: The N-terminal half of the protein contains the conserved
CC       domain II which is required for the correct degradation of the protein
CC       through the SCF-mediated ubiquitin-proteasome pathway. Interactions
CC       between Aux/IAA proteins and auxin response factors (ARFs) occur
CC       through their C-terminal dimerization domains III and IV.
CC   -!- MISCELLANEOUS: Lacks the EAR-like motif (Domain I) which is one of the
CC       conserved features of the Aux/IAA family.
CC   -!- SIMILARITY: Belongs to the Aux/IAA family. {ECO:0000305}.
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DR   EMBL; AB011482; BAB08779.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED96901.1; -; Genomic_DNA.
DR   EMBL; AY669804; AAT67088.1; -; mRNA.
DR   RefSeq; NP_200552.1; NM_125125.3.
DR   AlphaFoldDB; Q9FKM7; -.
DR   SMR; Q9FKM7; -.
DR   BioGRID; 21092; 48.
DR   IntAct; Q9FKM7; 47.
DR   STRING; 3702.AT5G57420.1; -.
DR   PaxDb; Q9FKM7; -.
DR   PRIDE; Q9FKM7; -.
DR   EnsemblPlants; AT5G57420.1; AT5G57420.1; AT5G57420.
DR   GeneID; 835848; -.
DR   Gramene; AT5G57420.1; AT5G57420.1; AT5G57420.
DR   KEGG; ath:AT5G57420; -.
DR   Araport; AT5G57420; -.
DR   TAIR; locus:2174562; AT5G57420.
DR   eggNOG; ENOG502S02T; Eukaryota.
DR   HOGENOM; CLU_135891_0_1_1; -.
DR   InParanoid; Q9FKM7; -.
DR   OMA; SFEPERH; -.
DR   OrthoDB; 1449173at2759; -.
DR   PhylomeDB; Q9FKM7; -.
DR   PRO; PR:Q9FKM7; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FKM7; baseline and differential.
DR   Genevisible; Q9FKM7; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0009733; P:response to auxin; TAS:TAIR.
DR   InterPro; IPR033389; AUX/IAA_dom.
DR   InterPro; IPR003311; AUX_IAA.
DR   InterPro; IPR000270; PB1_dom.
DR   PANTHER; PTHR31734; PTHR31734; 1.
DR   Pfam; PF02309; AUX_IAA; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   1: Evidence at protein level;
KW   Auxin signaling pathway; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..171
FT                   /note="Auxin-responsive protein IAA33"
FT                   /id="PRO_0000112859"
FT   DOMAIN          72..162
FT                   /note="PB1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   171 AA;  18942 MW;  B41460826FFE9BDC CRC64;
     MNSFEPQSQD SLQRRFHQDN STTQQPRDTT TPFIPKPASK NHNNSNSSSG AAGRSFQGFG
     LNVEDDLVSS VVPPVTVVLE GRSICQRISL DKHGSYQSLA SALRQMFVDG ADSTDDLDLS
     NAIPGHLIAY EDMENDLLLA GDLTWKDFVR VAKRIRILPV KGNTRQVKRN E