IAN11_ARATH
ID IAN11_ARATH Reviewed; 335 AA.
AC Q9T0F2;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Immune-associated nucleotide-binding protein 11 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN11 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN11 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At4g09930 {ECO:0000312|Araport:AT4G09930};
GN ORFNames=T5L19.60 {ECO:0000312|EMBL:CAB39617.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolide, nematode infection and cold
CC treatment. Down-regulated by aphid infection, 2-aminoethoxyvinylglycine
CC (AVG), high CO(2), isoxaben, and propiconazole treatments.
CC {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
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DR EMBL; AL049481; CAB39617.1; -; Genomic_DNA.
DR EMBL; AL161516; CAB78116.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82813.1; -; Genomic_DNA.
DR EMBL; AY122913; AAM67446.1; -; mRNA.
DR PIR; T03997; T03997.
DR RefSeq; NP_192731.1; NM_117061.2.
DR AlphaFoldDB; Q9T0F2; -.
DR SMR; Q9T0F2; -.
DR STRING; 3702.AT4G09930.1; -.
DR iPTMnet; Q9T0F2; -.
DR PaxDb; Q9T0F2; -.
DR PRIDE; Q9T0F2; -.
DR EnsemblPlants; AT4G09930.1; AT4G09930.1; AT4G09930.
DR GeneID; 826582; -.
DR Gramene; AT4G09930.1; AT4G09930.1; AT4G09930.
DR KEGG; ath:AT4G09930; -.
DR Araport; AT4G09930; -.
DR TAIR; locus:2140548; AT4G09930.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_0_1_1; -.
DR InParanoid; Q9T0F2; -.
DR OMA; YHCLNNE; -.
DR OrthoDB; 1108753at2759; -.
DR PhylomeDB; Q9T0F2; -.
DR PRO; PR:Q9T0F2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9T0F2; baseline and differential.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..335
FT /note="Immune-associated nucleotide-binding protein 11"
FT /id="PRO_0000438033"
FT DOMAIN 24..231
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 33..40
FT /note="G1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 60..64
FT /note="G2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 82..85
FT /note="G3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 152..155
FT /note="G4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 189..191
FT /note="G5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT COILED 279..331
FT /evidence="ECO:0000255"
FT BINDING 33..41
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 54
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 190
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
SQ SEQUENCE 335 AA; 37801 MW; 4CE437F60E5C4C3C CRC64;
MGGGLVEVDV QTGQDACESD LPMKPSRTLV LIGCSGNGKS ATGNSILRSE AFKSKGQAAA
VTKECELKST KRPNGQIINV IDTPGLFSLF PSNESTIREI LKCSHLAKEG IDAVLMVFSL
RSRLTEEEKS VPFVLKTLFG DSIFDYLIVV FTNEDSLIDD NVTINEYLEG SPDFKEILAA
CNNRMVLFEN RLRTSKRKKA KQVQKLLDLV EEVERKNNNK PFLFDLSHES MESEAVVDEK
AKKIRAMKSN YTKQEMSNWK EEEVNSPLAK KVEKVIETTS LLEQKLNQEQ NARLEAEKRA
NKLHEESSEE IKILKEKLER AQKELEKRDQ GCIIL
