IAN1_ARATH
ID IAN1_ARATH Reviewed; 225 AA.
AC Q9C8U2; Q9LQ35;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Immune-associated nucleotide-binding protein 1 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN1 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN1 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At1g33830 {ECO:0000312|Araport:AT1G33830};
GN ORFNames=T3M13.15 {ECO:0000312|EMBL:AAG52209.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- TISSUE SPECIFICITY: Mostly expressed in pollen.
CC {ECO:0000305|PubMed:17723251}.
CC -!- DEVELOPMENTAL STAGE: Expressed at the early flowering stage and at the
CC late stage of silique development. {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolides. Down-regulated by 2-
CC aminoethoxyvinylglycine (AVG), high CO(2), isoxaben, and propiconazole
CC treatments. {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF97280.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC010164; AAF97280.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC022288; AAG52209.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31630.1; -; Genomic_DNA.
DR PIR; A86462; A86462.
DR RefSeq; NP_174645.1; NM_103105.1.
DR AlphaFoldDB; Q9C8U2; -.
DR SMR; Q9C8U2; -.
DR STRING; 3702.AT1G33830.1; -.
DR PaxDb; Q9C8U2; -.
DR PRIDE; Q9C8U2; -.
DR EnsemblPlants; AT1G33830.1; AT1G33830.1; AT1G33830.
DR GeneID; 840278; -.
DR Gramene; AT1G33830.1; AT1G33830.1; AT1G33830.
DR KEGG; ath:AT1G33830; -.
DR Araport; AT1G33830; -.
DR TAIR; locus:2012678; AT1G33830.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_3_3_1; -.
DR InParanoid; Q9C8U2; -.
DR OMA; TENMHRK; -.
DR OrthoDB; 1108753at2759; -.
DR PhylomeDB; Q9C8U2; -.
DR PRO; PR:Q9C8U2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8U2; differential.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..225
FT /note="Immune-associated nucleotide-binding protein 1"
FT /id="PRO_0000438025"
FT DOMAIN 6..214
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 15..22
FT /note="G1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 42..46
FT /note="G2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 64..67
FT /note="G3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 134..137
FT /note="G4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 173..175
FT /note="G5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT BINDING 15..23
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 174
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
SQ SEQUENCE 225 AA; 25668 MW; 2DDBE4B96B816DBD CRC64;
MAEQECPVTN LLLLGRSENG KSSTGNTIIG EKYFEVNLFG RDMDQRCKMF RALIEDGPII
NVIDTPGLLE SSVSGDYLSK EIMNCLTMAE EGIHAVLFVL SITNRISQRE EFTFNTLQQI
FDDKILDYFI VVFTGGDELE ADNQTLDDYL REGCPEFLTR VLKLCGGRKV LFNNKTKDKG
KRNKQLNQLL AHVTDIRQQN GGIPYTENMH RKIKFKNLKY SNVKL
