IAN2_ARATH
ID IAN2_ARATH Reviewed; 234 AA.
AC Q9C8U5;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Immune-associated nucleotide-binding protein 2 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN2 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN2 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At1g33880 {ECO:0000312|Araport:AT1G33880};
GN ORFNames=T3M13.10 {ECO:0000312|EMBL:AAG52216.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- TISSUE SPECIFICITY: Mostly expressed in pollen. Also detected in
CC lateral roots and radicles. {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolides. Down-regulated by 2-
CC aminoethoxyvinylglycine (AVG), high CO(2), isoxaben, and propiconazole
CC treatments. {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
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DR EMBL; AC022288; AAG52216.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31636.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM57911.1; -; Genomic_DNA.
DR PIR; E86462; E86462.
DR RefSeq; NP_001319139.1; NM_001333070.1.
DR RefSeq; NP_174650.1; NM_103110.1.
DR AlphaFoldDB; Q9C8U5; -.
DR SMR; Q9C8U5; -.
DR PaxDb; Q9C8U5; -.
DR PRIDE; Q9C8U5; -.
DR EnsemblPlants; AT1G33880.1; AT1G33880.1; AT1G33880.
DR EnsemblPlants; AT1G33880.2; AT1G33880.2; AT1G33880.
DR GeneID; 840285; -.
DR Gramene; AT1G33880.1; AT1G33880.1; AT1G33880.
DR Gramene; AT1G33880.2; AT1G33880.2; AT1G33880.
DR KEGG; ath:AT1G33880; -.
DR Araport; AT1G33880; -.
DR TAIR; locus:2203812; AT1G33880.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_3_3_1; -.
DR InParanoid; Q9C8U5; -.
DR OMA; SEGAFMH; -.
DR OrthoDB; 1092873at2759; -.
DR PhylomeDB; Q9C8U5; -.
DR PRO; PR:Q9C8U5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8U5; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0034605; P:cellular response to heat; IGI:TAIR.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IGI:TAIR.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..234
FT /note="Immune-associated nucleotide-binding protein 2"
FT /id="PRO_0000438026"
FT DOMAIN 21..223
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT BINDING 30..38
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 51
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 183
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
SQ SEQUENCE 234 AA; 26378 MW; 84D9D7204A23473A CRC64;
MGTSVSKPVS DDKKKGTSVS KPVKNIVLVG RSVNGICTTG NNILGQNKFG SEGAFMHCQM
YSTTTPDGQM INVIKTPGMF DLSVSEDYIS KEIINCLTLA EEGVHAVLFV LSMKNRITQE
EEYALNTLQR IFGSKILEYL IFLLIDGEKF EAKEFEDYFP ECCPEFLMRV LRFCNGRKVL
FNNMTNDEGV KAEQVNQVMA HVAAISKKND EKPYTEDMYR NIKVNTFFSL IAFI
