IAN3_ARATH
ID IAN3_ARATH Reviewed; 334 AA.
AC Q9C8U6;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Immune-associated nucleotide-binding protein 3 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN3 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN3 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At1g33890 {ECO:0000312|Araport:AT1G33890};
GN ORFNames=T3M13.9 {ECO:0000312|EMBL:AAG52210.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- TISSUE SPECIFICITY: Mostly expressed in pollen. Also detected in
CC lateral roots and radicles. {ECO:0000305|PubMed:17723251}.
CC -!- DEVELOPMENTAL STAGE: Highest expression levels in young seedlings and
CC much lower expression abundance in the later developmental stages.
CC {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolides and nematode infection. Down-
CC regulated by 2-aminoethoxyvinylglycine (AVG), high CO(2), isoxaben, and
CC propiconazole treatments. {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
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DR EMBL; AC022288; AAG52210.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31637.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59627.1; -; Genomic_DNA.
DR PIR; F86462; F86462.
DR RefSeq; NP_001319140.1; NM_001333071.1.
DR RefSeq; NP_174651.1; NM_103111.2.
DR AlphaFoldDB; Q9C8U6; -.
DR SMR; Q9C8U6; -.
DR STRING; 3702.AT1G33890.1; -.
DR PaxDb; Q9C8U6; -.
DR PRIDE; Q9C8U6; -.
DR EnsemblPlants; AT1G33890.1; AT1G33890.1; AT1G33890.
DR EnsemblPlants; AT1G33890.2; AT1G33890.2; AT1G33890.
DR GeneID; 840286; -.
DR Gramene; AT1G33890.1; AT1G33890.1; AT1G33890.
DR Gramene; AT1G33890.2; AT1G33890.2; AT1G33890.
DR KEGG; ath:AT1G33890; -.
DR Araport; AT1G33890; -.
DR TAIR; locus:2203802; AT1G33890.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_0_1_1; -.
DR InParanoid; Q9C8U6; -.
DR OMA; EHMIALF; -.
DR OrthoDB; 1092873at2759; -.
DR PhylomeDB; Q9C8U6; -.
DR PRO; PR:Q9C8U6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8U6; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0034605; P:cellular response to heat; IGI:TAIR.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IGI:TAIR.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..334
FT /note="Immune-associated nucleotide-binding protein 3"
FT /id="PRO_0000438027"
FT DOMAIN 11..219
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 20..27
FT /note="G1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 47..51
FT /note="G2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 69..72
FT /note="G3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 139..142
FT /note="G4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 178..180
FT /note="G5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT COILED 272..306
FT /evidence="ECO:0000255"
FT BINDING 20..28
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 41
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 179
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
SQ SEQUENCE 334 AA; 37290 MW; 5D3A86E51A98E8D9 CRC64;
MNHSEQASAY KAVKNIVLVG RTGNGKSATG NSLIGKDVFV SEAKATGVTK TCQTYKAVTP
GGSRINVIDT PGLFDLSVSA EFISKEIINC LRLAEGGLHV VVLVLSVRTR ITQEEENTLS
TLQVLFGNEI LDYLIVLFTG GDELEANNQT LDDYFHQGCP YFLKTVLGLC DDRKVMFNNM
TKDKHKKVEQ VQQFLALVAK VEERNEGKPF RGKMYLEIKE ETEWLKKQKK AVEASNLGEA
ELAKMKKELQ MEHDTRMSQM EDMVKNMLKE TSAAHERMVS MLNENLENAH RENIDLRKAH
DHEQKKRMMI QLGLGVPGAL GMIAPAALAM CSIL
