IAN5_ARATH
ID IAN5_ARATH Reviewed; 301 AA.
AC Q9C8U8;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Immune-associated nucleotide-binding protein 5 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN5 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN5 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At1g33910 {ECO:0000312|Araport:AT1G33910};
GN ORFNames=T3M13.7 {ECO:0000312|EMBL:AAG52206.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- TISSUE SPECIFICITY: Expressed in pollen, cotyledons and lateral roots.
CC {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolide and heat treatment. Down-
CC regulated by 2-aminoethoxyvinylglycine (AVG), high CO(2), isoxaben, and
CC propiconazole treatments. {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
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DR EMBL; AC022288; AAG52206.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31639.1; -; Genomic_DNA.
DR EMBL; DQ056477; AAY78634.1; -; mRNA.
DR PIR; H86462; H86462.
DR RefSeq; NP_174653.1; NM_103113.1.
DR AlphaFoldDB; Q9C8U8; -.
DR SMR; Q9C8U8; -.
DR STRING; 3702.AT1G33910.1; -.
DR PaxDb; Q9C8U8; -.
DR PRIDE; Q9C8U8; -.
DR EnsemblPlants; AT1G33910.1; AT1G33910.1; AT1G33910.
DR GeneID; 840288; -.
DR Gramene; AT1G33910.1; AT1G33910.1; AT1G33910.
DR KEGG; ath:AT1G33910; -.
DR Araport; AT1G33910; -.
DR TAIR; locus:2203792; AT1G33910.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_0_1_1; -.
DR InParanoid; Q9C8U8; -.
DR OMA; ESCYTSK; -.
DR OrthoDB; 1108753at2759; -.
DR PhylomeDB; Q9C8U8; -.
DR PRO; PR:Q9C8U8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8U8; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0034605; P:cellular response to heat; IGI:TAIR.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IGI:TAIR.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 2: Evidence at transcript level;
KW GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..301
FT /note="Immune-associated nucleotide-binding protein 5"
FT /id="PRO_0000438029"
FT DOMAIN 11..214
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 20..27
FT /note="G1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 46..50
FT /note="G2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 63..66
FT /note="G3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 133..136
FT /note="G4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 172..174
FT /note="G5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT BINDING 20..28
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 173
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
SQ SEQUENCE 301 AA; 33679 MW; D26CF235861C7633 CRC64;
MSDRAQPSAS EPVRNIVLVG PTGNGKSSTG NSLIGKEVFI LETVECKTCK AKTLDGQIIN
VIDTPGLFDL SVSTDYMNKE IINCLTLTDG GLHAVVLVLS VGTDILKEEE AALNKLQLLF
GSKIVDYLVV LFTGGDVLEK ENKTLDDYLS RGCPEFLKTV LRLCGGRRVL FNNKTTDEVK
KIEQVKQLLA HVEAIENLNG GKALFTEEND LNEKRQGEML MEQEMEVQSK KPENTEVEEM
KKQLEISYGQ QMNMMAQMVE DTLKESSASH ERMLLALKDK VERSYLENED MHNETKRCNI
L
