IAN7_ARATH
ID IAN7_ARATH Reviewed; 311 AA.
AC Q9C8V2; Q1PFP4;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Immune-associated nucleotide-binding protein 7 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN7 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN7 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At1g33950 {ECO:0000312|Araport:AT1G33950};
GN ORFNames=T3M13.3 {ECO:0000312|EMBL:AAG52215.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9C8V2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9C8V2-2; Sequence=VSP_058601;
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolides. Down-regulated by 2-
CC aminoethoxyvinylglycine (AVG), high CO(2), isoxaben, and propiconazole
CC treatments. {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
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DR EMBL; AC022288; AAG52215.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31645.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31646.1; -; Genomic_DNA.
DR EMBL; DQ056478; AAY78635.1; -; mRNA.
DR EMBL; DQ446319; ABE65683.1; -; mRNA.
DR RefSeq; NP_001185133.1; NM_001198204.2. [Q9C8V2-2]
DR RefSeq; NP_001319142.1; NM_001333074.1. [Q9C8V2-1]
DR AlphaFoldDB; Q9C8V2; -.
DR SMR; Q9C8V2; -.
DR PaxDb; Q9C8V2; -.
DR PRIDE; Q9C8V2; -.
DR EnsemblPlants; AT1G33950.1; AT1G33950.1; AT1G33950. [Q9C8V2-1]
DR EnsemblPlants; AT1G33950.2; AT1G33950.2; AT1G33950. [Q9C8V2-2]
DR GeneID; 840292; -.
DR Gramene; AT1G33950.1; AT1G33950.1; AT1G33950. [Q9C8V2-1]
DR Gramene; AT1G33950.2; AT1G33950.2; AT1G33950. [Q9C8V2-2]
DR KEGG; ath:AT1G33950; -.
DR Araport; AT1G33950; -.
DR TAIR; locus:2203817; AT1G33950.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_0_1_1; -.
DR InParanoid; Q9C8V2; -.
DR OMA; QKGSREW; -.
DR OrthoDB; 1092873at2759; -.
DR PhylomeDB; Q9C8V2; -.
DR PRO; PR:Q9C8V2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8V2; baseline and differential.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; GTP-binding; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..311
FT /note="Immune-associated nucleotide-binding protein 7"
FT /id="PRO_0000438031"
FT DOMAIN 14..222
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 23..30
FT /note="G1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 50..54
FT /note="G2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 72..75
FT /note="G3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 142..145
FT /note="G4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 181..183
FT /note="G5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT COILED 218..295
FT /evidence="ECO:0000255"
FT BINDING 23..31
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 44
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 182
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT VAR_SEQ 75..80
FT /note="Missing (in isoform 2)"
FT /id="VSP_058601"
SQ SEQUENCE 311 AA; 34622 MW; 8C4306E72ACB3DCB CRC64;
MNKGGAQQKG HSSKQAENIV LVGRTGNGKS ATGNSLIGKK VFASKAHASG VTMKCQTHGV
VTKDGHKINV IDTPGLFDLS VSAEYISKEI VRCLTLAEGG IHAVLLVLSA RTRITQEEEN
TLRTLQALFG SQILDYVVVV FTGGDVLEEC KETLEDYLGR DCPTFIKEVM RMSSNRKVVI
DNKTHDEGKK AEQVHKLLSL VDDIRRSKCG EAYTDDTYHM IKEESEKLRK HHEELESKNY
SEECAAEMKN QSLILYKENL KQMSEQLEKK LKDAAEAQEK ALSKMTQENN ELNLALKIHI
PLPPITPCNI L
