IAN9_ARATH
ID IAN9_ARATH Reviewed; 342 AA.
AC F4HT21; F4HT25; Q8H7C8; Q9C8V3; Q9FE56;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Immune-associated nucleotide-binding protein 9 {ECO:0000303|PubMed:17723251};
DE Short=AtIAN9 {ECO:0000303|PubMed:17723251};
DE AltName: Full=AIG1-like protein {ECO:0000305};
GN Name=IAN9 {ECO:0000303|PubMed:17723251};
GN OrderedLocusNames=At1g33970 {ECO:0000312|Araport:AT1G33970};
GN ORFNames=F12G12.21 {ECO:0000312|EMBL:AAG12538.1},
GN T15K4.2 {ECO:0000312|EMBL:AAG12846.1},
GN T3M13.1 {ECO:0000312|EMBL:AAG52214.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RA Stracke R., Palme K.;
RT "Signal peptide selection derived cDNAs from Arabidopsis thaliana leaves
RT and guard cells.";
RL Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17723251; DOI=10.1016/j.jplph.2007.06.002;
RA Liu C., Wang T., Zhang W., Li X.;
RT "Computational identification and analysis of immune-associated nucleotide
RT gene family in Arabidopsis thaliana.";
RL J. Plant Physiol. 165:777-787(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=F4HT21-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4HT21-2; Sequence=VSP_058602, VSP_058603;
CC -!- TISSUE SPECIFICITY: Mainly expressed in leaves.
CC {ECO:0000305|PubMed:17723251}.
CC -!- INDUCTION: Up-regulated by brassinolides. Down-regulated by 2-
CC aminoethoxyvinylglycine (AVG), high CO(2), isoxaben, and propiconazole
CC treatments. {ECO:0000305|PubMed:17723251}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG12538.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAG12846.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAM65167.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAN60299.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC015446; AAG12538.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC022288; AAG52214.1; -; Genomic_DNA.
DR EMBL; AC079286; AAG12846.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE31648.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31649.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31650.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31651.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31652.1; -; Genomic_DNA.
DR EMBL; AF083741; AAN60299.1; ALT_INIT; mRNA.
DR EMBL; AY087627; AAM65167.1; ALT_INIT; mRNA.
DR PIR; D86463; D86463.
DR RefSeq; NP_001031136.1; NM_001036059.2. [F4HT21-1]
DR RefSeq; NP_001031137.1; NM_001036060.3. [F4HT21-2]
DR RefSeq; NP_001077647.1; NM_001084178.2. [F4HT21-1]
DR RefSeq; NP_001185134.1; NM_001198205.2. [F4HT21-1]
DR RefSeq; NP_564431.1; NM_103119.5. [F4HT21-1]
DR AlphaFoldDB; F4HT21; -.
DR SMR; F4HT21; -.
DR STRING; 3702.AT1G33970.2; -.
DR PaxDb; F4HT21; -.
DR PRIDE; F4HT21; -.
DR ProteomicsDB; 232143; -. [F4HT21-1]
DR EnsemblPlants; AT1G33970.1; AT1G33970.1; AT1G33970. [F4HT21-1]
DR EnsemblPlants; AT1G33970.2; AT1G33970.2; AT1G33970. [F4HT21-1]
DR EnsemblPlants; AT1G33970.3; AT1G33970.3; AT1G33970. [F4HT21-2]
DR EnsemblPlants; AT1G33970.4; AT1G33970.4; AT1G33970. [F4HT21-1]
DR EnsemblPlants; AT1G33970.5; AT1G33970.5; AT1G33970. [F4HT21-1]
DR GeneID; 840294; -.
DR Gramene; AT1G33970.1; AT1G33970.1; AT1G33970. [F4HT21-1]
DR Gramene; AT1G33970.2; AT1G33970.2; AT1G33970. [F4HT21-1]
DR Gramene; AT1G33970.3; AT1G33970.3; AT1G33970. [F4HT21-2]
DR Gramene; AT1G33970.4; AT1G33970.4; AT1G33970. [F4HT21-1]
DR Gramene; AT1G33970.5; AT1G33970.5; AT1G33970. [F4HT21-1]
DR KEGG; ath:AT1G33970; -.
DR Araport; AT1G33970; -.
DR TAIR; locus:2009041; AT1G33970.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_0_1_1; -.
DR InParanoid; F4HT21; -.
DR OMA; PITATCE; -.
DR OrthoDB; 1092873at2759; -.
DR PRO; PR:F4HT21; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HT21; baseline and differential.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:1900425; P:negative regulation of defense response to bacterium; IMP:TAIR.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903; PTHR10903; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; GTP-binding; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..342
FT /note="Immune-associated nucleotide-binding protein 9"
FT /id="PRO_0000438032"
FT DOMAIN 22..229
FT /note="AIG1-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 31..38
FT /note="G1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 58..62
FT /note="G2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 80..83
FT /note="G3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 149..152
FT /note="G4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT REGION 188..190
FT /note="G5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT COILED 276..342
FT /evidence="ECO:0000255"
FT BINDING 31..39
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 52
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT BINDING 189
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250|UniProtKB:Q8NHV1"
FT VAR_SEQ 276
FT /note="E -> I (in isoform 2)"
FT /id="VSP_058602"
FT VAR_SEQ 277..342
FT /note="Missing (in isoform 2)"
FT /id="VSP_058603"
FT CONFLICT 214
FT /note="Q -> H (in Ref. 3; AAN60299)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 342 AA; 38815 MW; 498ED011EDACD2BE CRC64;
MSLLDMGGDM MEDDWEFASS SNPKRTLVLV GRTGNGKSAT GNSILGRKAF RSRARTVGVT
STCESQRVVQ EDGDIINVVD TPGLFDLSTA ADFIGKEIVR CISLAEDGIH AILLVFSVRR
LAEEEQTVLS FLQALFGSKI ADYMIVVFTG GDELEENEET LEEYLADYCP EFLKEILGIC
DNRLVLFNNK TTDKVKKAEQ VQKLLSLVES VVKQNNGKPY SDELFHELQE EAIKLRDQKK
EVELLQGYSN NEIDEFKKQI DMSYDRQLSR ITEMVETKLR DTAKRLEQQL GEEQAARLEA
EKRANEVQKR SSDEIKKLRE NLERAEKETK ELQKKLGKCI NL
