IBAG_ECOLI
ID IBAG_ECOLI Reviewed; 84 AA.
AC P0A9W6; P43781; P76672; Q2M922;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Acid stress protein IbaG {ECO:0000305};
GN Name=ibaG {ECO:0000303|PubMed:22534295}; Synonyms=yrbA;
GN OrderedLocusNames=b3190, JW3157;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=B / BL21;
RX PubMed=10493123;
RX DOI=10.1002/(sici)1522-2683(19990801)20:11<2181::aid-elps2181>3.0.co;2-q;
RA Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B.;
RT "Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite
RT chromatography.";
RL Electrophoresis 20:2181-2195(1999).
RN [4]
RP FUNCTION, INDUCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=MG1693;
RX PubMed=22534295; DOI=10.4014/jmb.1107.07037;
RA Guinote I.B., Moreira R.N., Freire P., Arraiano C.M.;
RT "Characterization of the BolA homolog IbaG: a new gene involved in acid
RT resistance.";
RL J. Microbiol. Biotechnol. 22:484-493(2012).
RN [5]
RP STRUCTURE BY NMR OF 1-84.
RG Northeast structural genomics consortium (NESG);
RT "Solution structure of protein yrbA from Escherichia coli.";
RL Submitted (FEB-2003) to the PDB data bank.
CC -!- FUNCTION: Involved in cell resistance against acid stress.
CC {ECO:0000269|PubMed:22534295}.
CC -!- INTERACTION:
CC P0A9W6; P0AC69: grxD; NbExp=4; IntAct=EBI-1131877, EBI-545828;
CC -!- INDUCTION: Induced by acidic stress during exponential phase.
CC {ECO:0000269|PubMed:22534295}.
CC -!- DISRUPTION PHENOTYPE: Deletion mutants grow faster and have higher
CC viabilities in rich media, but have lower viabilities than the wild
CC type in the late stationary phase. {ECO:0000269|PubMed:22534295}.
CC -!- SIMILARITY: Belongs to the BolA/IbaG family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA57991.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U18997; AAA57991.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC76222.2; -; Genomic_DNA.
DR EMBL; AP009048; BAE77234.1; -; Genomic_DNA.
DR RefSeq; NP_417657.2; NC_000913.3.
DR RefSeq; WP_000429656.1; NZ_STEB01000012.1.
DR PDB; 1NY8; NMR; -; A=1-84.
DR PDBsum; 1NY8; -.
DR AlphaFoldDB; P0A9W6; -.
DR BMRB; P0A9W6; -.
DR SMR; P0A9W6; -.
DR BioGRID; 4261275; 37.
DR ComplexPortal; CPX-5899; ibaG-grxD iron-sulfur cluster assembly complex.
DR DIP; DIP-48231N; -.
DR IntAct; P0A9W6; 4.
DR STRING; 511145.b3190; -.
DR jPOST; P0A9W6; -.
DR PaxDb; P0A9W6; -.
DR PRIDE; P0A9W6; -.
DR EnsemblBacteria; AAC76222; AAC76222; b3190.
DR EnsemblBacteria; BAE77234; BAE77234; BAE77234.
DR GeneID; 66672908; -.
DR GeneID; 947958; -.
DR KEGG; ecj:JW3157; -.
DR KEGG; eco:b3190; -.
DR PATRIC; fig|511145.12.peg.3284; -.
DR EchoBASE; EB2648; -.
DR eggNOG; COG5007; Bacteria.
DR HOGENOM; CLU_109462_4_1_6; -.
DR InParanoid; P0A9W6; -.
DR OMA; QIYAHLN; -.
DR PhylomeDB; P0A9W6; -.
DR BioCyc; EcoCyc:G7657-MON; -.
DR EvolutionaryTrace; P0A9W6; -.
DR PRO; PR:P0A9W6; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:1990229; C:iron-sulfur cluster assembly complex; IPI:ComplexPortal.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:EcoCyc.
DR GO; GO:0045454; P:cell redox homeostasis; IC:ComplexPortal.
DR GO; GO:0097533; P:cellular stress response to acid chemical; IEP:EcoCyc.
DR GO; GO:0055072; P:iron ion homeostasis; IC:ComplexPortal.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IC:ComplexPortal.
DR Gene3D; 3.30.300.90; -; 1.
DR InterPro; IPR002634; BolA.
DR InterPro; IPR036065; BolA-like_sf.
DR Pfam; PF01722; BolA; 1.
DR PIRSF; PIRSF003113; BolA; 1.
DR SUPFAM; SSF82657; SSF82657; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Stress response.
FT CHAIN 1..84
FT /note="Acid stress protein IbaG"
FT /id="PRO_0000201218"
FT HELIX 4..14
FT /evidence="ECO:0007829|PDB:1NY8"
FT STRAND 17..35
FT /evidence="ECO:0007829|PDB:1NY8"
FT STRAND 38..40
FT /evidence="ECO:0007829|PDB:1NY8"
FT HELIX 42..50
FT /evidence="ECO:0007829|PDB:1NY8"
FT TURN 51..53
FT /evidence="ECO:0007829|PDB:1NY8"
FT HELIX 54..60
FT /evidence="ECO:0007829|PDB:1NY8"
FT STRAND 63..69
FT /evidence="ECO:0007829|PDB:1NY8"
FT HELIX 72..80
FT /evidence="ECO:0007829|PDB:1NY8"
SQ SEQUENCE 84 AA; 9452 MW; CCC3072D5FFA98E3 CRC64;
MENNEIQSVL MNALSLQEVH VSGDGSHFQV IAVGELFDGM SRVKKQQTVY GPLMEYIADN
RIHAVSIKAY TPAEWARDRK LNGF
