ID   APBC_ECOLI              Reviewed;         369 AA.
AC   P0AF08; P21590; Q2MAW5;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Iron-sulfur cluster carrier protein {ECO:0000255|HAMAP-Rule:MF_02040};
GN   Name=mrp; OrderedLocusNames=b2113, JW2100;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2259334; DOI=10.1007/bf00315804;
RA   Dardel F., Panvert M., Fayat G.;
RT   "Transcription and regulation of expression of the Escherichia coli
RT   methionyl-tRNA synthetase gene.";
RL   Mol. Gen. Genet. 223:121-133(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / BHB2600;
RA   Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA   Church G.M.;
RT   "Automated multiplex sequencing of the E.coli genome.";
RL   Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Binds and transfers iron-sulfur (Fe-S) clusters to target
CC       apoproteins. Can hydrolyze ATP. {ECO:0000255|HAMAP-Rule:MF_02040}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_02040}.
CC   -!- SIMILARITY: Belongs to the Mrp/NBP35 ATP-binding proteins family.
CC       {ECO:0000255|HAMAP-Rule:MF_02040}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA60527.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U00007; AAA60527.1; ALT_INIT; Genomic_DNA.
DR   EMBL; X55791; CAA39316.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75174.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76591.1; -; Genomic_DNA.
DR   RefSeq; NP_416616.4; NC_000913.3.
DR   RefSeq; WP_001005448.1; NZ_STEB01000002.1.
DR   AlphaFoldDB; P0AF08; -.
DR   SMR; P0AF08; -.
DR   BioGRID; 4259514; 62.
DR   IntAct; P0AF08; 6.
DR   STRING; 511145.b2113; -.
DR   jPOST; P0AF08; -.
DR   PaxDb; P0AF08; -.
DR   PRIDE; P0AF08; -.
DR   EnsemblBacteria; AAC75174; AAC75174; b2113.
DR   EnsemblBacteria; BAE76591; BAE76591; BAE76591.
DR   GeneID; 66673991; -.
DR   GeneID; 946627; -.
DR   KEGG; ecj:JW2100; -.
DR   KEGG; eco:b2113; -.
DR   PATRIC; fig|1411691.4.peg.134; -.
DR   EchoBASE; EB0606; -.
DR   eggNOG; COG0489; Bacteria.
DR   HOGENOM; CLU_024839_0_0_6; -.
DR   InParanoid; P0AF08; -.
DR   OMA; NMAYFTP; -.
DR   PhylomeDB; P0AF08; -.
DR   BioCyc; EcoCyc:EG10611-MON; -.
DR   PRO; PR:P0AF08; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140663; F:ATP-dependent FeS chaperone activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_02040; Mrp_NBP35; 1.
DR   InterPro; IPR034904; FSCA_dom_sf.
DR   InterPro; IPR019591; Mrp/NBP35_ATP-bd.
DR   InterPro; IPR000808; Mrp_CS.
DR   InterPro; IPR044304; NUBPL-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR033756; YlxH/NBP35.
DR   PANTHER; PTHR42961; PTHR42961; 1.
DR   Pfam; PF10609; ParA; 1.
DR   SUPFAM; SSF117916; SSF117916; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01215; MRP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Hydrolase; Iron; Iron-sulfur; Metal-binding;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..369
FT                   /note="Iron-sulfur cluster carrier protein"
FT                   /id="PRO_0000184932"
FT   BINDING         115..122
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02040"
SQ   SEQUENCE   369 AA;  39938 MW;  F3437F3A6408042E CRC64;
     MNEQSQAKSP EALRAMVAGT LANFQHPTLK HNLTTLKALH HVAWMDDTLH VELVMPFVWH
     SAFEELKEQC SAELLRITGA KAIDWKLSHN IATLKRVKNQ PGINGVKNII AVSSGKGGVG
     KSSTAVNLAL ALAAEGAKVG ILDADIYGPS IPTMLGAENQ RPTSPDGTHM APIMSHGLAT
     NSIGYLVTDD NAMVWRGPMA SKALMQMLQE TLWPDLDYLV LDMPPGTGDI QLTLAQNIPV
     TGAVVVTTPQ DIALIDAKKG IVMFEKVEVP VLGIVENMSV HICSNCGHHE PIFGTGGAEK
     LAEKYHTQLL GQMPLHISLR EDLDKGTPTV ISRPESEFTA IYRQLADRVA AQLYWQGEVI
     PGEISFRAV