ID   IBB2_WHEAT              Reviewed;          53 AA.
AC   P09864;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Bowman-Birk type proteinase inhibitor II-4;
DE   Flags: Fragment;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=3818572; DOI=10.1093/oxfordjournals.jbchem.a121810;
RA   Odani S., Koide T., Ono T.;
RT   "Wheat germ trypsin inhibitors. Isolation and structural characterization
RT   of single-headed and double-headed inhibitors of the Bowman-Birk type.";
RL   J. Biochem. 100:975-983(1986).
CC   -!- SIMILARITY: Belongs to the Bowman-Birk serine protease inhibitor
CC       family. {ECO:0000305}.
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DR   PIR; B25507; B25507.
DR   MEROPS; I12.010; -.
DR   PRIDE; P09864; -.
DR   Proteomes; UP000019116; Unplaced.
DR   ExpressionAtlas; P09864; baseline.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   CDD; cd00023; BBI; 1.
DR   Gene3D; 2.10.69.10; -; 1.
DR   InterPro; IPR035995; Bowman-Birk_prot_inh.
DR   InterPro; IPR000877; Prot_inh_BBI.
DR   Pfam; PF00228; Bowman-Birk_leg; 1.
DR   SMART; SM00269; BowB; 1.
DR   SUPFAM; SSF57247; SSF57247; 1.
DR   PROSITE; PS00281; BOWMAN_BIRK; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Protease inhibitor;
KW   Reference proteome; Serine protease inhibitor.
FT   CHAIN           <1..>53
FT                   /note="Bowman-Birk type proteinase inhibitor II-4"
FT                   /id="PRO_0000105859"
FT   SITE            15..16
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250"
FT   SITE            41..42
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250"
FT   DISULFID        8..23
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        13..21
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        30..37
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        34..49
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   NON_TER         1
FT   NON_TER         53
SQ   SEQUENCE   53 AA;  5953 MW;  824F3FDBAA35BBE2 CRC64;
     ATRPWKCCDR AICTKSFPPM CRCMDMVEQC AATCKKCGPA TSDSSRRVCE DXY