ID   APBC_METJA              Reviewed;         290 AA.
AC   Q57731;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Iron-sulfur cluster carrier protein {ECO:0000255|HAMAP-Rule:MF_02040, ECO:0000303|PubMed:19114487};
GN   OrderedLocusNames=MJ0283;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
RN   [2]
RP   FUNCTION.
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=19114487; DOI=10.1128/jb.01469-08;
RA   Boyd J.M., Drevland R.M., Downs D.M., Graham D.E.;
RT   "Archaeal ApbC/Nbp35 homologs function as iron-sulfur cluster carrier
RT   proteins.";
RL   J. Bacteriol. 191:1490-1497(2009).
CC   -!- FUNCTION: Binds and transfers iron-sulfur (Fe-S) clusters to target
CC       apoproteins. Can hydrolyze ATP. {ECO:0000255|HAMAP-Rule:MF_02040,
CC       ECO:0000269|PubMed:19114487}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_02040}.
CC   -!- SIMILARITY: Belongs to the Mrp/NBP35 ATP-binding proteins family.
CC       {ECO:0000255|HAMAP-Rule:MF_02040}.
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DR   EMBL; L77117; AAB98271.1; -; Genomic_DNA.
DR   PIR; D64335; D64335.
DR   RefSeq; WP_010869781.1; NC_000909.1.
DR   AlphaFoldDB; Q57731; -.
DR   SMR; Q57731; -.
DR   STRING; 243232.MJ_0283; -.
DR   EnsemblBacteria; AAB98271; AAB98271; MJ_0283.
DR   GeneID; 1451138; -.
DR   KEGG; mja:MJ_0283; -.
DR   eggNOG; arCOG00585; Archaea.
DR   HOGENOM; CLU_024839_0_1_2; -.
DR   InParanoid; Q57731; -.
DR   OMA; NMAYFTP; -.
DR   OrthoDB; 32313at2157; -.
DR   PhylomeDB; Q57731; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140663; F:ATP-dependent FeS chaperone activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_02040; Mrp_NBP35; 1.
DR   InterPro; IPR019591; Mrp/NBP35_ATP-bd.
DR   InterPro; IPR000808; Mrp_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR033756; YlxH/NBP35.
DR   PANTHER; PTHR23264; PTHR23264; 1.
DR   Pfam; PF10609; ParA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01215; MRP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Hydrolase; Iron; Iron-sulfur; Metal-binding;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..290
FT                   /note="Iron-sulfur cluster carrier protein"
FT                   /id="PRO_0000184953"
FT   BINDING         47..54
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02040"
SQ   SEQUENCE   290 AA;  31243 MW;  D5C0E3A15DB728EF CRC64;
     MAECDGKCDT CPSKNTCPDT KKLLAQQDAK IRENMSKIKH KIVILSGKGG VGKSTVTVNL
     AAALNLMGKK VGVLDADIHG PNIPKMLGVE NTQPMAGPAG IFPIVTKDGI KTMSIGYLLP
     DDKTPVIWRG PKVSGAIRQF LSDVVWGELD YLLIDTPPGT GDEQLTIMQS IPDIDGAIIV
     TTPEEVSVLD VKKSIMMAKM LNIPIIGIIE NMSGFVCPYC NKVVDIFGRG GGEKAAKELG
     VEFLGRIPLD IKAREASDKG IPMVLLDCKA SEEFKKIVKR IVEKVEGKKE