ID   IBBWP_MAIZE             Reviewed;         102 AA.
AC   P31862;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Bowman-Birk type wound-induced proteinase inhibitor WIP1;
DE   Flags: Precursor;
GN   Name=WIP1;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Brio;
RX   PubMed=8358030; DOI=10.1007/bf00027365;
RA   Rohrmeier T., Lehle L.;
RT   "WIP1, a wound-inducible gene from maize with homology to Bowman-Birk
RT   proteinase inhibitors.";
RL   Plant Mol. Biol. 22:783-792(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Brio; TISSUE=Seedling;
RX   PubMed=8495751; DOI=10.1016/0014-5793(93)81451-5;
RA   Eckelkamp C., Ehmann B., Schopfer P.;
RT   "Wound-induced systemic accumulation of a transcript coding for a Bowman-
RT   Birk trypsin inhibitor-related protein in maize (Zea mays L.) seedlings.";
RL   FEBS Lett. 323:73-76(1993).
CC   -!- INDUCTION: By wounding.
CC   -!- SIMILARITY: Belongs to the Bowman-Birk serine protease inhibitor
CC       family. {ECO:0000305}.
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DR   EMBL; X71396; CAA50519.1; -; mRNA.
DR   PIR; S36236; S36236.
DR   AlphaFoldDB; P31862; -.
DR   STRING; 4577.GRMZM2G156632_P01; -.
DR   MEROPS; I12.019; -.
DR   PaxDb; P31862; -.
DR   PRIDE; P31862; -.
DR   MaizeGDB; 46002; -.
DR   eggNOG; ENOG502R3J3; Eukaryota.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P31862; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   CDD; cd00023; BBI; 1.
DR   Gene3D; 2.10.69.10; -; 1.
DR   InterPro; IPR035995; Bowman-Birk_prot_inh.
DR   InterPro; IPR000877; Prot_inh_BBI.
DR   InterPro; IPR044167; WIP1.
DR   PANTHER; PTHR37378; PTHR37378; 1.
DR   Pfam; PF00228; Bowman-Birk_leg; 1.
DR   SMART; SM00269; BowB; 1.
DR   SUPFAM; SSF57247; SSF57247; 1.
DR   PROSITE; PS00281; BOWMAN_BIRK; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Protease inhibitor; Reference proteome;
KW   Serine protease inhibitor; Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..102
FT                   /note="Bowman-Birk type wound-induced proteinase inhibitor
FT                   WIP1"
FT                   /id="PRO_0000003270"
FT   SITE            52..53
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250"
FT   DISULFID        46..102
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        47..60
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        50..98
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        67..74
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   DISULFID        71..90
FT                   /evidence="ECO:0000250|UniProtKB:P80321"
FT   CONFLICT        11
FT                   /note="L -> V (in Ref. 2; no nucleotide entry)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   102 AA;  10976 MW;  2BDBEC44FA79C179 CRC64;
     MKSSPHLVLI LCLQAALVMG VFAALAKENA MVESKAIDIN PGQLKCCTNC NFSFSGLYTC
     DDVKKDCDPV CKKCVVAVHA SYSGNNKFRC TDTFLGMCGP KC