IBD2_ASHGO
ID IBD2_ASHGO Reviewed; 344 AA.
AC Q754P2;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Protein IBD2;
GN Name=IBD2; OrderedLocusNames=AFR030C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Part of a checkpoint which monitors spindle integrity and
CC prevents premature exit from mitosis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle pole
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IBD2 family. {ECO:0000305}.
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DR EMBL; AE016819; AAS53401.1; -; Genomic_DNA.
DR RefSeq; NP_985577.1; NM_210931.1.
DR AlphaFoldDB; Q754P2; -.
DR STRING; 33169.AAS53401; -.
DR EnsemblFungi; AAS53401; AAS53401; AGOS_AFR030C.
DR GeneID; 4621817; -.
DR KEGG; ago:AGOS_AFR030C; -.
DR eggNOG; ENOG502RXXW; Eukaryota.
DR HOGENOM; CLU_067888_0_0_1; -.
DR InParanoid; Q754P2; -.
DR OMA; PKNMIKW; -.
DR Proteomes; UP000000591; Chromosome VI.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR InterPro; IPR026231; IBD2.
DR PRINTS; PR02099; PROTEINIBD2.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Mitosis;
KW Reference proteome.
FT CHAIN 1..344
FT /note="Protein IBD2"
FT /id="PRO_0000333334"
FT REGION 71..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..344
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 38183 MW; D079A31B6CB82747 CRC64;
MSEPERASIE FVSESDSIDF GIMMKKGVKA LTDILANHLQ HDPEWKNERS MKFVFKNQNG
ELQPVLNRTA RLEDEGVGPS PDDGQVVDGE ETASEQDKLA EANCSDGSST GDLQLDDPES
EVLFDYSLDH LPNISYTPDP TIGKHVMEMI ESLLPKGAPY REKVLNTMKN NVQGAGMSTA
GTAAVETIQH TAGSTISEPA MSYECDRDLG IAESDDWEHQ QFAQPHHGTL EADTVAEGHH
RCQSRSSESQ HAGHQRAGQE YLYECKPKAR PDFHALTMFD PLEQPLCMFC EYYLVFGEPP
RQMIKWYNKY GSSSGGPSAG SQQGNKGWNG NKKKKKKKGK KGKR
