ID   IBMP_CAMV4              Reviewed;         520 AA.
AC   P22547;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Transactivator/viroplasmin protein;
DE            Short=Tav;
DE   AltName: Full=Inclusion body matrix protein;
GN   ORFNames=ORF VI;
OS   Cauliflower mosaic virus (strain D4) (CaMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10642;
OH   NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=3725; Raphanus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=2134858; DOI=10.1094/mpmi-3-341;
RA   Daubert S., Routh J.;
RT   "Point mutations in cauliflower mosaic virus gene VI confer host-specific
RT   symptom changes.";
RL   Mol. Plant Microbe Interact. 3:341-345(1990).
CC   -!- FUNCTION: Enhances the ribosomal termination-reinitiation event leading
CC       to the translation of major open reading frames on the polycistronic
CC       viral RNAs. {ECO:0000250|UniProtKB:P03558}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Note=Found in cytoplasmic
CC       occlusion bodies.
CC   -!- MISCELLANEOUS: The inclusion bodies are the site of viral DNA
CC       synthesis, virion assembly and accumulation in the infected cell.
CC   -!- SIMILARITY: Belongs to the caulimoviridae viroplasmin family.
CC       {ECO:0000305}.
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DR   EMBL; M23620; AAA03526.1; -; Unassigned_RNA.
DR   SMR; P22547; -.
DR   PRIDE; P22547; -.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.970.10; -; 1.
DR   InterPro; IPR009027; Ribosomal_L9/RNase_H1_N.
DR   InterPro; IPR011320; RNase_H1_N.
DR   InterPro; IPR037056; RNase_H1_N_sf.
DR   Pfam; PF01693; Cauli_VI; 1.
DR   SUPFAM; SSF55658; SSF55658; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Translation regulation.
FT   CHAIN           1..520
FT                   /note="Transactivator/viroplasmin protein"
FT                   /id="PRO_0000222037"
FT   REGION          32..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          487..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  58140 MW;  6884E2952B6AA5D9 CRC64;
     MENIEKLLMQ EKILMLELDL VKAKISLARA NGSSQQGELS LHRETPEKEE AVHSALATFT
     PTQVKAIPEQ TAPGKESTNP LMASILPKDM NSVQTEIRLK RPSDFLRPYQ GISIPQKSEL
     NSTVTLHGVE SGIQHPHINY YVVYNGPHAG IYDDWGCTKA ATNGVPGVAQ KKFATITEAR
     AAADAYTTSQ QTDRLNFIPK GEAQLKPKSF AKALTSPSKQ KAHWLTLGTK RPSSDPAPKE
     ISFAPEITMD DFLYLYDLGR KFDGEGDDTM FTTDNEKISL FNFRKNADPQ MVREAYAAGL
     IKTIYPSNNL QEIKYLPKKV KDAVKRFRTN CIKNTEKDIF LKIRSTIPVW TIQGLLHKPR
     QVIEIGVSKK VVPTESKAME SKIQIEDLTE LAVKTGEQFI QSLLRLNDKK KIFVNMVEHD
     TLVYSKNIKD TVSEDQRAIE TFQQRVISGN LLGFHCPAIC HFIERTVEKE GGTYKCHHCD
     KGKAIIQDAS TDSGPKDGPP PTRSIVEKED VPTTSSKQVD