ID   APBC_PYRFU              Reviewed;         295 AA.
AC   Q8U1R0;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Iron-sulfur cluster carrier protein {ECO:0000255|HAMAP-Rule:MF_02040};
GN   OrderedLocusNames=PF1145;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- FUNCTION: Binds and transfers iron-sulfur (Fe-S) clusters to target
CC       apoproteins. Can hydrolyze ATP. {ECO:0000255|HAMAP-Rule:MF_02040}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_02040}.
CC   -!- SIMILARITY: Belongs to the Mrp/NBP35 ATP-binding proteins family.
CC       {ECO:0000255|HAMAP-Rule:MF_02040}.
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DR   EMBL; AE009950; AAL81269.1; -; Genomic_DNA.
DR   RefSeq; WP_011012285.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U1R0; -.
DR   SMR; Q8U1R0; -.
DR   STRING; 186497.PF1145; -.
DR   PRIDE; Q8U1R0; -.
DR   EnsemblBacteria; AAL81269; AAL81269; PF1145.
DR   GeneID; 41712954; -.
DR   KEGG; pfu:PF1145; -.
DR   PATRIC; fig|186497.12.peg.1206; -.
DR   eggNOG; arCOG00585; Archaea.
DR   HOGENOM; CLU_024839_0_1_2; -.
DR   OMA; NMAYFTP; -.
DR   OrthoDB; 32313at2157; -.
DR   PhylomeDB; Q8U1R0; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140663; F:ATP-dependent FeS chaperone activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_02040; Mrp_NBP35; 1.
DR   InterPro; IPR019591; Mrp/NBP35_ATP-bd.
DR   InterPro; IPR000808; Mrp_CS.
DR   InterPro; IPR044304; NUBPL-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR033756; YlxH/NBP35.
DR   PANTHER; PTHR42961; PTHR42961; 1.
DR   Pfam; PF10609; ParA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01215; MRP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Hydrolase; Iron; Iron-sulfur; Metal-binding;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Iron-sulfur cluster carrier protein"
FT                   /id="PRO_0000184955"
FT   BINDING         38..45
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02040"
SQ   SEQUENCE   295 AA;  32010 MW;  10F73C4A7B24937C CRC64;
     MTIKAPTLNV PGLGVDPLTQ RIKEKEKKWK YKIAVLSGKG GVGKSTVAVN LTAALAKMGY
     FVGILDADIH GPNVAKMFGI GNTDIYAEKF EDGHFEMIPP TVDFMGQVTP IKVMSMGMMV
     PEDQPIIWRG SLVTKAIKQL LGDVMWGELD FMIIDFPPGT GDEILTVVQS IQLDAAIVVT
     TPQEVALLDT GKAVNMMKKM EVPYIAVIEN MSYLICPHCG NKIDIFGEGG GEKLAEKEGV
     DFLGKVPIDL KAREASDLGI PIVLYGDTPA AKAFMEIAEK LVNKLKEIKG DGREK