ID   ICA_APIME               Reviewed;         223 AA.
AC   Q5BLY4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Icarapin-like;
DE   AltName: Full=Venom carbohydrate-rich protein;
DE   Flags: Precursor;
OS   Apis mellifera (Honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Apidae;
OC   Apis.
OX   NCBI_TaxID=7460;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Hoffman D.R., Weimer E.T., Sakell R.H., Schmidt M.;
RT   "Sequence and characterization of honeybee venom acid phosphatase.";
RL   J. Allergy Clin. Immunol. 115:S107-S107(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17073008; DOI=10.1038/nature05260;
RG   Honeybee genome sequencing consortium;
RT   "Insights into social insects from the genome of the honeybee Apis
RT   mellifera.";
RL   Nature 443:931-949(2006).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC   -!- ALLERGEN: Causes an allergic reaction in human. {ECO:0000250}.
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DR   EMBL; AY939856; AAX33236.1; -; mRNA.
DR   AlphaFoldDB; Q5BLY4; -.
DR   STRING; 7460.GB40759-PA; -.
DR   Allergome; 8204; Api m 10.
DR   Allergome; 8205; Api m 10.0101.
DR   eggNOG; ENOG502T7XG; Eukaryota.
DR   Proteomes; UP000005203; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Allergen; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..223
FT                   /note="Icarapin-like"
FT                   /id="PRO_0000402384"
FT   REGION          186..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..204
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        126
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        142
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        168
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        193
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   223 AA;  24819 MW;  9BD51D084DFBFB28 CRC64;
     MKTLGVLFIA AWFIACTHSF PGAHDEDSKE ERKNVDTVLV LPSIERDQMM AATFDFPSLS
     FEDSDEGSNW NWNTLLRPNF LDGWYQTLQS AISAHMKKVR EQMAGILSRI PEQGVVNWNK
     IPEGANTTST TKIIDGHVVT INETTYTDGS DDYSTLIRVR VIDVRPQNET ILTTVSSEAD
     SDVTTLPTLI GKNETSTQSS RSVESVEDFD NEIPKNQGDV LTA