ID   ICI1_PHAAN              Reviewed;          92 AA.
AC   P16064;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Subtilisin inhibitor 1;
DE   AltName: Full=ASI-I;
DE   AltName: Full=Subtilisin inhibitor I;
DE   Contains:
DE     RecName: Full=Subtilisin inhibitor 2;
DE     AltName: Full=ASI-II;
DE     AltName: Full=Subtilisin inhibitor II;
OS   Phaseolus angularis (Azuki bean) (Vigna angularis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX   NCBI_TaxID=3914;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=2628417; DOI=10.1093/oxfordjournals.jbchem.a122955;
RA   Nozawa H., Yamagata H., Aizono Y., Yoshikawa M., Iwasaki T.;
RT   "The complete amino acid sequence of a subtilisin inhibitor from adzuki
RT   beans (Vigna angularis).";
RL   J. Biochem. 106:1003-1008(1989).
CC   -!- FUNCTION: Inhibitor of subtilisin.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I13 (potato type I serine
CC       protease inhibitor) family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; JX0089; JX0089.
DR   AlphaFoldDB; P16064; -.
DR   SMR; P16064; -.
DR   MEROPS; I13.007; -.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009611; P:response to wounding; IEA:InterPro.
DR   InterPro; IPR000864; Prot_inh_pot1.
DR   InterPro; IPR036354; Prot_inh_pot1_sf.
DR   PANTHER; PTHR33091; PTHR33091; 1.
DR   Pfam; PF00280; potato_inhibit; 1.
DR   PRINTS; PR00292; POTATOINHBTR.
DR   SUPFAM; SSF54654; SSF54654; 1.
DR   PROSITE; PS00285; POTATO_INHIBITOR; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Protease inhibitor; Serine protease inhibitor.
FT   CHAIN           1..92
FT                   /note="Subtilisin inhibitor 1"
FT                   /id="PRO_0000025296"
FT   CHAIN           20..92
FT                   /note="Subtilisin inhibitor 2"
FT                   /id="PRO_0000025297"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            68..69
FT                   /note="Reactive bond"
SQ   SEQUENCE   92 AA;  10384 MW;  3AF21936DF567D45 CRC64;
     QEQGTNPSQE QNVPLPRNYK QALETNTPTK TSWPELVGVT AEQAETKIKE EMVDVQIQVS
     PHDSFVTADY NPKRVRLYVD ESNKVTRTPS IG