ID   ICI1_SOLLC              Reviewed;         111 AA.
AC   P05118;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Wound-induced proteinase inhibitor 1;
DE   AltName: Full=Wound-induced proteinase inhibitor I;
DE   Flags: Precursor;
GN   Name=PIIF;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2987227; DOI=10.1016/s0021-9258(18)88817-2;
RA   Graham J.S., Pearce G., Merryweather J., Titani K., Ericsson L., Ryan C.A.;
RT   "Wound-induced proteinase inhibitors from tomato leaves. I. The cDNA-
RT   deduced primary structure of pre-inhibitor I and its post-translational
RT   processing.";
RL   J. Biol. Chem. 260:6555-6560(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Bonny Best; TISSUE=Leaf;
RX   PubMed=3463966; DOI=10.1073/pnas.83.19.7277;
RA   Lee J.S., Brown W.E., Graham J.S., Pearce G., Fox E.A., Dreher T.W.,
RA   Ahern K.G., Pearson G.D., Ryan C.A.;
RT   "Molecular characterization and phylogenetic studies of a wound-inducible
RT   proteinase inhibitor I gene in Lycopersicon species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 83:7277-7281(1986).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- INDUCTION: By wounding.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I13 (potato type I serine
CC       protease inhibitor) family. {ECO:0000305}.
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DR   EMBL; K03290; AAA34199.1; -; mRNA.
DR   EMBL; M13938; AAA34200.1; -; Genomic_DNA.
DR   PIR; A25046; A24048.
DR   RefSeq; NP_001295870.1; NM_001308941.1.
DR   AlphaFoldDB; P05118; -.
DR   SMR; P05118; -.
DR   STRING; 4081.Solyc09g084470.2.1; -.
DR   MEROPS; I13.002; -.
DR   MEROPS; I13.010; -.
DR   PaxDb; P05118; -.
DR   PRIDE; P05118; -.
DR   GeneID; 543954; -.
DR   KEGG; sly:543954; -.
DR   eggNOG; ENOG502SU6V; Eukaryota.
DR   HOGENOM; CLU_158942_4_1_1; -.
DR   InParanoid; P05118; -.
DR   OrthoDB; 1582946at2759; -.
DR   PhylomeDB; P05118; -.
DR   Proteomes; UP000004994; Unplaced.
DR   ExpressionAtlas; P05118; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009611; P:response to wounding; IEA:InterPro.
DR   InterPro; IPR000864; Prot_inh_pot1.
DR   InterPro; IPR036354; Prot_inh_pot1_sf.
DR   PANTHER; PTHR33091; PTHR33091; 1.
DR   Pfam; PF00280; potato_inhibit; 1.
DR   PRINTS; PR00292; POTATOINHBTR.
DR   SUPFAM; SSF54654; SSF54654; 1.
DR   PROSITE; PS00285; POTATO_INHIBITOR; 1.
PE   2: Evidence at transcript level;
KW   Protease inhibitor; Reference proteome; Secreted;
KW   Serine protease inhibitor; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   PROPEP          24..36
FT                   /id="PRO_0000025298"
FT   CHAIN           37..111
FT                   /note="Wound-induced proteinase inhibitor 1"
FT                   /id="PRO_0000025299"
FT   SITE            87..88
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   111 AA;  12585 MW;  124BAC3400E9F0D6 CRC64;
     MESKFAHIIV FFLLATSFET LMARKEIDGP EVIELLKEFD SNLMCEGKQM WPELIGVPTK
     LAKEIIEKEN PSITNIPILL SGSPITLDYL CDRVRLFDNI LGFVVQMPVV T