ID   ICI3_HORVU              Reviewed;          72 AA.
AC   P08626;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Subtilisin-chymotrypsin inhibitor-2B;
DE            Short=CI-2B;
DE   Flags: Fragment;
OS   Hordeum vulgare (Barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=4513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Hiproly, and cv. Sundance;
RX   PubMed=3106042; DOI=10.1111/j.1432-1033.1987.tb11199.x;
RA   Williamson M.S., Forde J., Buxton B., Kreis M.;
RT   "Nucleotide sequence of barley chymotrypsin inhibitor-2 (CI-2) and its
RT   expression in normal and high-lysine barley.";
RL   Eur. J. Biochem. 165:99-106(1987).
CC   -!- FUNCTION: Inhibits both subtilisin and chymotrypsin.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I13 (potato type I serine
CC       protease inhibitor) family. {ECO:0000305}.
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DR   EMBL; X05405; CAA28989.1; -; mRNA.
DR   PIR; B29537; B29537.
DR   AlphaFoldDB; P08626; -.
DR   SMR; P08626; -.
DR   MEROPS; I13.003; -.
DR   ExpressionAtlas; P08626; baseline.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009611; P:response to wounding; IEA:InterPro.
DR   InterPro; IPR000864; Prot_inh_pot1.
DR   InterPro; IPR036354; Prot_inh_pot1_sf.
DR   PANTHER; PTHR33091; PTHR33091; 1.
DR   Pfam; PF00280; potato_inhibit; 1.
DR   PRINTS; PR00292; POTATOINHBTR.
DR   SUPFAM; SSF54654; SSF54654; 1.
PE   2: Evidence at transcript level;
KW   Protease inhibitor; Serine protease inhibitor.
FT   CHAIN           <1..72
FT                   /note="Subtilisin-chymotrypsin inhibitor-2B"
FT                   /id="PRO_0000217650"
FT   SITE            48..49
FT                   /note="Reactive bond"
FT   NON_TER         1
SQ   SEQUENCE   72 AA;  8296 MW;  1E234A15438062B1 CRC64;
     DCLCDCQNQK TEWPELVEKS VEEAKKVILQ DKPEAQIIVL PVGTIVTMEY RIDRVRLFVD
     RLDNIAQVPR VG