ID   ICP22_EHV1B             Reviewed;         293 AA.
AC   Q6S6W5; P28940;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   23-FEB-2022, entry version 52.
DE   RecName: Full=Transcriptional regulator ICP22 homolog;
DE   AltName: Full=IR4 protein;
DE   AltName: Full=Immediate-early protein IE68;
DE   AltName: Full=In vitro host-range factor;
DE   AltName: Full=ORF S1-2;
GN   Name=IR4; OrderedLocusNames=65;
OS   Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=31520;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA   Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus-1.";
RL   Virology 189:304-316(1992).
CC   -!- SIMILARITY: Belongs to the herpesviridae ICP22 family. {ECO:0000305}.
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DR   EMBL; AY665713; AAT67322.1; -; Genomic_DNA.
DR   EMBL; AY665713; AAT67336.1; -; Genomic_DNA.
DR   PIR; B36802; EDBEF7.
DR   RefSeq; YP_053109.1; NC_001491.2.
DR   RefSeq; YP_053123.1; NC_001491.2.
DR   PRIDE; Q6S6W5; -.
DR   GeneID; 2948568; -.
DR   GeneID; 2948573; -.
DR   KEGG; vg:2948568; -.
DR   KEGG; vg:2948573; -.
DR   Proteomes; UP000001189; Genome.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR   InterPro; IPR003403; IE68.
DR   Pfam; PF02479; Herpes_IE68; 1.
PE   3: Inferred from homology;
KW   Early protein; Reference proteome.
FT   CHAIN           1..293
FT                   /note="Transcriptional regulator ICP22 homolog"
FT                   /id="PRO_0000115839"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        195..212
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        236..268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..283
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   293 AA;  32117 MW;  3D9E89D028276D7F CRC64;
     MPHGQPCGAC DGSCRMAQRG TPSTSPLIPS LTPSPPAGDP SPRSSQRIDA VRVPARLPGG
     SDHPEYGMPL SPRALRPYLA RGPGAFCAPP WRPDVNRLAG DVNRLFRGIS TSSIHVTEDS
     RTLRRALLDF YAMGYTHTRP TLECWQSLLQ LLPEQSFPLR ATLRALNSED RYEQRFLEPP
     SDPPNTLFGE ECDVSGDESP SEEEEEDEAS GESSVSEFSP EEETASSEYD SFSDVGEDDS
     SCTGKWSSSE SESDSESDAP TNNHHPTTRA SAAKKRRKRQ PPKGERPTKS ARR