ID   ICP22_EHV4              Reviewed;         273 AA.
AC   P18346;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   02-JUN-2021, entry version 42.
DE   RecName: Full=Transcriptional regulator ICP22 homolog;
DE   AltName: Full=Immediate-early protein IE68;
DE   AltName: Full=ORF4;
DE   Flags: Fragment;
OS   Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=10333;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2839595; DOI=10.1099/0022-1317-69-7-1575;
RA   Cullinane A.A., Rixon F.J., Davison A.J.;
RT   "Characterization of the genome of equine herpesvirus 1 subtype 2.";
RL   J. Gen. Virol. 69:1575-1590(1988).
CC   -!- SIMILARITY: Belongs to the herpesviridae ICP22 family. {ECO:0000305}.
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DR   EMBL; D00318; BAA00221.1; -; Genomic_DNA.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR   InterPro; IPR003403; IE68.
DR   Pfam; PF02479; Herpes_IE68; 1.
PE   3: Inferred from homology;
KW   Early protein.
FT   CHAIN           <1..273
FT                   /note="Transcriptional regulator ICP22 homolog"
FT                   /id="PRO_0000115841"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..207
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..250
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..273
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   273 AA;  29833 MW;  8F3A3B8626984D2E CRC64;
     GSCRMSQRGA PSTSPIIPSL SPSSGGNPSP RSSQRIDSVR VPARLPGGSD HPEYGLPLSP
     RSLRPYLSRG PGAFCAPPWR PDVNRLAGDV NRLFRGISTS SIHVTEDSRV LRRVLLDFYA
     MGYTHARPTL ECWQALLQLM PEQSLPLRAT LRAINSEDKY EQRFLDPPSK PPKTLFGEEC
     EVSGDESPSE EEEASGNSTI SEFSPEEESA SSDFESFSDE EDDSCCTGKW SSSESDSEAD
     VPTNPPTTRA RAAQKRRGRP VPKGGRPAKS ARR