ID   ICP22_SHV21             Reviewed;         407 AA.
AC   Q01042;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   02-JUN-2021, entry version 55.
DE   RecName: Full=Transcriptional regulator ICP22 homolog;
DE   AltName: Full=Immediate-early protein;
GN   Name=73; Synonyms=ECLF1;
OS   Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus.
OX   NCBI_TaxID=10383;
OH   NCBI_TaxID=9521; Saimiri sciureus (Common squirrel monkey).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1321287; DOI=10.1128/jvi.66.8.5047-5058.1992;
RA   Albrecht J.-C., Nicholas J., Biller D., Cameron K.R., Biesinger B.,
RA   Newman C., Wittmann S., Craxton M.A., Coleman H., Fleckenstein B.,
RA   Honess R.W.;
RT   "Primary structure of the herpesvirus saimiri genome.";
RL   J. Virol. 66:5047-5058(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1314457; DOI=10.1016/0042-6822(92)90759-i;
RA   Nicholas J., Cameron K.R., Coleman H., Newman C., Honess R.W.;
RT   "Analysis of nucleotide sequence of the rightmost 43 kbp of herpesvirus
RT   saimiri (HVS) L-DNA: general conservation of genetic organization between
RT   HVS and Epstein-Barr virus.";
RL   Virology 188:296-310(1992).
CC   -!- SIMILARITY: Belongs to the herpesviridae ICP22 family. {ECO:0000305}.
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DR   EMBL; X64346; CAA45696.1; -; Genomic_DNA.
DR   EMBL; M86409; AAA46149.1; -; Genomic_DNA.
DR   EMBL; S76368; AAB21116.1; -; Genomic_DNA.
DR   RefSeq; NP_040275.1; NC_001350.1.
DR   SMR; Q01042; -.
DR   GeneID; 1682516; -.
DR   KEGG; vg:1682516; -.
DR   Proteomes; UP000000587; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.30.70.390; -; 1.
DR   InterPro; IPR037007; EBNA1_DNA-bd_sf.
PE   3: Inferred from homology;
KW   Early protein; Reference proteome.
FT   CHAIN           1..407
FT                   /note="Transcriptional regulator ICP22 homolog"
FT                   /id="PRO_0000115844"
FT   REGION          34..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..240
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  46618 MW;  FFD399CA82CE136C CRC64;
     MAPRRRKAKR RRHTLRSECK DKCKCHVQCY VSPRKRRRKL KPQGDDDINT THQQQAALTE
     EQRREEVEEE GEERERRGEE EREGEGGEEG EGREEAEEEE AEEKEAEEEE AEEAEEEAEE
     EEAEEAEAEE EEAEEEEAEE EEAEEAEEEE AEEAEEEAEE EEAEEEAEEE AEEAEEAEEE
     AEEEAEEAEE AEEAEEAEEE AEEAEEEAEE AEEEAEEAEE AEEAEEAEEE AEEAEEEEEE
     AGPSTPRLPH YKVVGQKPST QPGGVPKLCL KMQPQHRSRL PKGKQSHDKV PKKYQARNKF
     FSQAAPSVLD LSPKSWCWVV DFWGPTDALY RLSRSLSFPG AVSSGIQTFP KGPHATGPWV
     YFITVYCRTF QTAKEVIKAQ KKYEKKYPRS AKLKASLGKF SKSLPIE