ID   ICP46_FRG3G             Reviewed;         395 AA.
AC   P14358; Q6GZN4;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 2.
DT   02-DEC-2020, entry version 41.
DE   RecName: Full=Immediate-early protein ICP-46;
GN   Name=ICR489;
OS   Frog virus 3 (isolate Goorha) (FV-3).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Alphairidovirinae; Ranavirus.
OX   NCBI_TaxID=654924;
OH   NCBI_TaxID=30343; Dryophytes versicolor (chameleon treefrog).
OH   NCBI_TaxID=8404; Lithobates pipiens (Northern leopard frog) (Rana pipiens).
OH   NCBI_TaxID=45438; Lithobates sylvaticus (Wood frog) (Rana sylvatica).
OH   NCBI_TaxID=8316; Notophthalmus viridescens (Eastern newt) (Triturus viridescens).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2831387; DOI=10.1128/jvi.62.4.1271-1277.1988;
RA   Beckman W., Tham T.N., Aubertin A.M., Willis D.B.;
RT   "Structure and regulation of the immediate-early frog virus 3 gene that
RT   encodes ICR489.";
RL   J. Virol. 62:1271-1277(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15165820; DOI=10.1016/j.virol.2004.02.019;
RA   Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.;
RT   "Comparative genomic analyses of frog virus 3, type species of the genus
RT   Ranavirus (family Iridoviridae).";
RL   Virology 323:70-84(2004).
CC   -!- SIMILARITY: Belongs to the IIV-6 393L family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA43824.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; M19872; AAA43824.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AY548484; AAT09751.1; -; Genomic_DNA.
DR   PIR; A29886; EDXFI3.
DR   RefSeq; YP_031670.1; NC_005946.1.
DR   GeneID; 2947810; -.
DR   KEGG; vg:2947810; -.
DR   Proteomes; UP000008770; Genome.
PE   3: Inferred from homology;
KW   Early protein; Reference proteome.
FT   CHAIN           1..395
FT                   /note="Immediate-early protein ICP-46"
FT                   /id="PRO_0000222388"
SQ   SEQUENCE   395 AA;  45543 MW;  58771A8C4E03FD7B CRC64;
     MANFVTDSRN GLTISCAPQD QSHLHPTIRA LVMEGDSVIF RGLPHPDIHR EAPPAGLRLK
     DCLVYDSYEG ALVNVFWHGG QWWFCTNKKL SIDRASWSAS PGSFKRAFVN CLRKMWRDDR
     SWADLFDRSY MPSFCDANLD KDLGYVFMVF DPEERIVCSD TEQRLRLLAT FDRCTNSHSY
     ECSLTLTCGT EVEVPRPICL KNEREFLLHL RSQDPCRVAG VVLIDALDIH YKILPSEYTK
     VLDARGEQPR LLNRMFQLME MGPEGEAHIE VLCRYFSDAR VAMERAWDVR ERIVQCYLDL
     TEPDSEPQVW MTRRLMEIVR GCRPGTERTM IDEFLRTMTT GQRKAFYKKH ACLAGGDNAW
     ISSDAPIKQA KTVQDLVEFP DDNCQDMDEL FVVRA