ID   ICR4_ARATH              Reviewed;         324 AA.
AC   Q9M9F9; F4IA81;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Interactor of constitutive active ROPs 4;
DE   AltName: Full=ROP-interactive partner 4;
GN   Name=ICR4; Synonyms=RIP4; OrderedLocusNames=At1g78430; ORFNames=F3F9.6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   INTERACTION WITH ARAC11, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19825600; DOI=10.1093/mp/ssn051;
RA   Li S., Gu Y., Yan A., Lord E., Yang Z.B.;
RT   "RIP1 (ROP Interactive Partner 1)/ICR1 marks pollen germination sites and
RT   may act in the ROP1 pathway in the control of polarized pollen growth.";
RL   Mol. Plant 1:1021-1035(2008).
CC   -!- FUNCTION: Acts as a scaffold, mediating interaction of ROPs with
CC       different proteins. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ARAC11 in vitro. {ECO:0000269|PubMed:19825600}.
CC   -!- SIMILARITY: Belongs to the ICR family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF71812.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC013430; AAF71812.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE36105.1; -; Genomic_DNA.
DR   PIR; G96812; G96812.
DR   RefSeq; NP_177964.2; NM_106490.4.
DR   AlphaFoldDB; Q9M9F9; -.
DR   SMR; Q9M9F9; -.
DR   BioGRID; 29398; 2.
DR   STRING; 3702.AT1G78430.1; -.
DR   iPTMnet; Q9M9F9; -.
DR   PaxDb; Q9M9F9; -.
DR   PRIDE; Q9M9F9; -.
DR   ProteomicsDB; 228770; -.
DR   EnsemblPlants; AT1G78430.1; AT1G78430.1; AT1G78430.
DR   GeneID; 844179; -.
DR   Gramene; AT1G78430.1; AT1G78430.1; AT1G78430.
DR   KEGG; ath:AT1G78430; -.
DR   Araport; AT1G78430; -.
DR   TAIR; locus:2032095; AT1G78430.
DR   eggNOG; ENOG502QVSP; Eukaryota.
DR   HOGENOM; CLU_043733_1_0_1; -.
DR   InParanoid; Q9M9F9; -.
DR   OMA; FACIFHE; -.
DR   OrthoDB; 1223458at2759; -.
DR   PRO; PR:Q9M9F9; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9M9F9; baseline and differential.
DR   Genevisible; Q9M9F9; AT.
DR   InterPro; IPR029688; ICR.
DR   PANTHER; PTHR34224; PTHR34224; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..324
FT                   /note="Interactor of constitutive active ROPs 4"
FT                   /id="PRO_0000220599"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          289..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          62..266
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        9..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..324
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   324 AA;  36057 MW;  8A95DF3FBC5AE626 CRC64;
     MPKPSIRGSE LPQRQSPRLR TSLLSTSSDP HHLSRPITDR SPKLGLDRRS PRSGGPHTDP
     LSQKKLGSRI SGLESQLGQA QEELRLLKQQ LAKAEAAKKR AQEELHRKKS KKPNTPAPER
     DDIPGDGHQE TDVFEVLDEK AKESEKTKND ELASKEDQIN VLKARLYDLE KERVSLSEEN
     ETLKDQLKKT DTEMSCAKAK EDEIASKVSQ IGEELEESNE TTAKLKKKLE SVEEAKETLE
     AEMKKLKVQT EQWRKAADAA AAVLSGGVEM NGRFSEQCGS MEKHFAGRFV GSPGMADDSD
     DGSGKRKSSG KKMFGDLWKK KGQK