ID   ID5B_ADEPA              Reviewed;          38 AA.
AC   P09942;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Trypsin inhibitor DE5 beta chain;
OS   Adenanthera pavonina (Sandal bead tree) (Condori wood).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Caesalpinioideae; mimosoid clade;
OC   Mimoseae; Adenanthera.
OX   NCBI_TaxID=3811;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Seed;
RA   Richardson M., Campos F.A.P., Xavier-Filho J., Macedo M.L.R., Maia G.M.C.,
RA   Yarwood A.;
RT   "The amino acid sequence and reactive (inhibitory) site of the major
RT   trypsin isoinhibitor (DE5) isolated from seeds of the Brazilian Carolina
RT   tree (Adenanthera pavonina L.).";
RL   Biochim. Biophys. Acta 872:134-140(1986).
CC   -!- FUNCTION: Inhibition of trypsin.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain linked by a disulfide
CC       bond.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I3 (leguminous Kunitz-
CC       type inhibitor) family. {ECO:0000305}.
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DR   PIR; B24376; B24376.
DR   AlphaFoldDB; P09942; -.
DR   SMR; P09942; -.
DR   MEROPS; I03.019; -.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR011065; Kunitz_inhibitor_STI-like_sf.
DR   InterPro; IPR002160; Prot_inh_Kunz-lg.
DR   Pfam; PF00197; Kunitz_legume; 1.
DR   SUPFAM; SSF50386; SSF50386; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Protease inhibitor;
KW   Serine protease inhibitor.
FT   CHAIN           1..38
FT                   /note="Trypsin inhibitor DE5 beta chain"
FT                   /id="PRO_0000083293"
FT   DISULFID        3
FT                   /note="Interchain (with alpha chain)"
FT                   /evidence="ECO:0000250"
FT   VARIANT         1
FT                   /note="L -> P"
SQ   SEQUENCE   38 AA;  4229 MW;  E51F7F924F53FAC7 CRC64;
     LECKDLGISI DDDNNRRLAV KEGDPLVVQF VNADREGN