IDGF_HELVI
ID IDGF_HELVI Reviewed; 37 AA.
AC P86357;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-MAR-2010, sequence version 1.
DT 25-MAY-2022, entry version 16.
DE RecName: Full=Chitinase-like protein {ECO:0000250|UniProtKB:Q9W303};
DE AltName: Full=Imaginal disk growth factor protein {ECO:0000250|UniProtKB:Q9W303};
DE Flags: Fragments;
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE.
RC TISSUE=Hemolymph;
RA Shelby K.S., Webb B.A.;
RL Submitted (SEP-2009) to UniProtKB.
CC -!- FUNCTION: Cooperates with insulin-like peptides to stimulate the
CC proliferation, polarization and motility of imaginal disk cells. May
CC act by stabilizing the binding of insulin-like peptides to its receptor
CC through a simultaneous interaction with both molecules to form a
CC multiprotein signaling complex (By similarity).
CC {ECO:0000250|UniProtKB:Q9W303}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9W303}.
CC Note=Secreted in hemolymph. It is probably transported to target
CC tissues via hemolymph. {ECO:0000250}.
CC -!- PTM: Glycosylated. {ECO:0000250|UniProtKB:Q23997}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. IDGF
CC subfamily. {ECO:0000255}.
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DR AlphaFoldDB; P86357; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR PROSITE; PS51910; GH18_2; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Direct protein sequencing; Glycoprotein; Secreted.
FT CHAIN <1..>37
FT /note="Chitinase-like protein"
FT /id="PRO_0000392513"
FT DOMAIN <1..>37
FT /note="GH18"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01258"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_CONS 17..18
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 37
SQ SEQUENCE 37 AA; 3849 MW; D475908D05E3E5B5 CRC64;
VLLSVGGDAD TESPEKKNLG GVSIVDLSMD DFRGLLT