ID   IDLC_CHLRE              Reviewed;         253 AA.
AC   Q39604; A8JDN3;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=28 kDa inner dynein arm light chain, axonemal;
DE   AltName: Full=p28;
GN   Name=IDA4; Synonyms=P28; ORFNames=CHLREDRAFT_132451;
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-17 AND
RP   175-193.
RX   PubMed=7579689; DOI=10.1091/mbc.6.6.697;
RA   LeDizet M., Piperno G.;
RT   "The light chain p28 associates with a subset of inner dynein arm heavy
RT   chains in Chlamydomonas axonemes.";
RL   Mol. Biol. Cell 6:697-711(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-503, and cw92;
RX   PubMed=17932292; DOI=10.1126/science.1143609;
RA   Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA   Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA   Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA   Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA   Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA   Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA   Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA   Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA   Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA   Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA   Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA   Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA   Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA   Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA   Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA   Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA   Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA   Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA   Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA   Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA   Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT   "The Chlamydomonas genome reveals the evolution of key animal and plant
RT   functions.";
RL   Science 318:245-250(2007).
RN   [3]
RP   MUTANTS IDA4.
RX   PubMed=7579690; DOI=10.1091/mbc.6.6.713;
RA   LeDizet M., Piperno G.;
RT   "ida4-1, ida4-2, and ida4-3 are intron splicing mutations affecting the
RT   locus encoding p28, a light chain of Chlamydomonas axonemal inner dynein
RT   arms.";
RL   Mol. Biol. Cell 6:713-723(1995).
CC   -!- FUNCTION: Plays a dynamic role in flagellar motility. May be necessary
CC       for stable assembly of a subset of inner dynein arms or for the binding
CC       of these arms to the outer doublet microtubules of the axoneme.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme.
CC       Note=Present along the entire length of the axoneme.
CC   -!- SIMILARITY: Belongs to the inner dynein arm light chain family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z48059; CAA88139.1; -; Genomic_DNA.
DR   EMBL; DS496163; EDO97971.1; -; Genomic_DNA.
DR   PIR; T08152; T08152.
DR   RefSeq; XP_001700527.1; XM_001700475.1.
DR   PDB; 7JU4; EM; 3.40 A; v/w=1-253.
DR   PDBsum; 7JU4; -.
DR   AlphaFoldDB; Q39604; -.
DR   SMR; Q39604; -.
DR   STRING; 3055.EDO97971; -.
DR   PRIDE; Q39604; -.
DR   GeneID; 5726078; -.
DR   eggNOG; KOG4001; Eukaryota.
DR   HOGENOM; CLU_072652_0_0_1; -.
DR   OrthoDB; 1375694at2759; -.
DR   GO; GO:0036156; C:inner dynein arm; IDA:GO_Central.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   GO; GO:0045504; F:dynein heavy chain binding; IPI:GO_Central.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IMP:GO_Central.
DR   GO; GO:0036159; P:inner dynein arm assembly; IMP:GO_Central.
DR   InterPro; IPR019347; Axonemal_dynein_light_chain.
DR   PANTHER; PTHR13183; PTHR13183; 1.
DR   Pfam; PF10211; Ax_dynein_light; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell projection; Cilium; Cilium biogenesis/degradation;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Direct protein sequencing; Dynein;
KW   Flagellum; Motor protein.
FT   CHAIN           1..253
FT                   /note="28 kDa inner dynein arm light chain, axonemal"
FT                   /id="PRO_0000114681"
FT   REGION          19..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          160..239
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   253 AA;  28653 MW;  B16D2ABA00A9F093 CRC64;
     MIPPLSSLVR YDNPVLVSTS KDKGKGAKGT PGKKGALPPV EQKPGLTQTE DILNSILPPR
     EWTEDGQLWV QYVSSTPATR LDVINLQEKL DQQLQQRQAR ETGICPIREE LYAQTFDELI
     RQVTINCAER GLLLLRVRDE MRMTIAAYQT LYESAVAFGI RKALQTEQGK SEMESRITQL
     EGDVKDLERQ VQEWKFKCEA IEKRESERRE VEAKKHKDEV AYLENYAKQL KQQLETFLVP
     AKKGAPGAPA AAT