IDLC_DROME
ID IDLC_DROME Reviewed; 250 AA.
AC Q9VGG6; A0AMZ0;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Putative inner dynein arm light chain, axonemal {ECO:0000305};
GN Name=Dnali1 {ECO:0000312|FlyBase:FBgn0037962};
GN ORFNames=CG6971 {ECO:0000312|FlyBase:FBgn0037962};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ZBMEL131, ZBMEL145, ZBMEL157, ZBMEL186, ZBMEL191, ZBMEL377,
RC ZBMEL384, ZBMEL398, ZBMEL82, ZBMEL84, and ZBMEL95;
RX PubMed=16951084; DOI=10.1534/genetics.106.058008;
RA Proeschel M., Zhang Z., Parsch J.;
RT "Widespread adaptive evolution of Drosophila genes with sex-biased
RT expression.";
RL Genetics 174:893-900(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Head;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- FUNCTION: May play a dynamic role in flagellar motility. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000250|UniProtKB:O14645}. Dynein axonemal particle
CC {ECO:0000250|UniProtKB:Q6GN86}.
CC -!- SIMILARITY: Belongs to the inner dynein arm light chain family.
CC {ECO:0000305}.
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DR EMBL; AM294028; CAL25932.1; -; Genomic_DNA.
DR EMBL; AM294029; CAL25933.1; -; Genomic_DNA.
DR EMBL; AM294030; CAL25934.1; -; Genomic_DNA.
DR EMBL; AM294031; CAL25935.1; -; Genomic_DNA.
DR EMBL; AM294032; CAL25936.1; -; Genomic_DNA.
DR EMBL; AM294033; CAL25937.1; -; Genomic_DNA.
DR EMBL; AM294034; CAL25938.1; -; Genomic_DNA.
DR EMBL; AM294035; CAL25939.1; -; Genomic_DNA.
DR EMBL; AM294036; CAL25940.1; -; Genomic_DNA.
DR EMBL; AM294037; CAL25941.1; -; Genomic_DNA.
DR EMBL; AM294038; CAL25942.1; -; Genomic_DNA.
DR EMBL; AE014297; AAF54716.1; -; Genomic_DNA.
DR EMBL; AY069202; AAL39347.1; -; mRNA.
DR RefSeq; NP_650128.1; NM_141871.3.
DR AlphaFoldDB; Q9VGG6; -.
DR SMR; Q9VGG6; -.
DR IntAct; Q9VGG6; 2.
DR STRING; 7227.FBpp0081988; -.
DR PaxDb; Q9VGG6; -.
DR DNASU; 41440; -.
DR EnsemblMetazoa; FBtr0082514; FBpp0081988; FBgn0037962.
DR GeneID; 41440; -.
DR KEGG; dme:Dmel_CG6971; -.
DR UCSC; CG6971-RA; d. melanogaster.
DR CTD; 7802; -.
DR FlyBase; FBgn0037962; Dnali1.
DR VEuPathDB; VectorBase:FBgn0037962; -.
DR eggNOG; KOG4001; Eukaryota.
DR GeneTree; ENSGT00390000003012; -.
DR HOGENOM; CLU_072652_0_0_1; -.
DR InParanoid; Q9VGG6; -.
DR OMA; INCTERG; -.
DR OrthoDB; 1375694at2759; -.
DR PhylomeDB; Q9VGG6; -.
DR BioGRID-ORCS; 41440; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 41440; -.
DR PRO; PR:Q9VGG6; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0037962; Expressed in testis and 12 other tissues.
DR ExpressionAtlas; Q9VGG6; baseline and differential.
DR Genevisible; Q9VGG6; DM.
DR GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR GO; GO:0120293; C:dynein axonemal particle; ISS:UniProtKB.
DR GO; GO:0030175; C:filopodium; IBA:GO_Central.
DR GO; GO:0036156; C:inner dynein arm; ISS:FlyBase.
DR GO; GO:0045504; F:dynein heavy chain binding; ISS:FlyBase.
DR GO; GO:0003341; P:cilium movement; ISS:FlyBase.
DR GO; GO:0036159; P:inner dynein arm assembly; ISS:FlyBase.
DR InterPro; IPR019347; Axonemal_dynein_light_chain.
DR PANTHER; PTHR13183; PTHR13183; 1.
DR Pfam; PF10211; Ax_dynein_light; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Coiled coil; Cytoplasm; Dynein; Motor protein;
KW Reference proteome.
FT CHAIN 1..250
FT /note="Putative inner dynein arm light chain, axonemal"
FT /id="PRO_0000114679"
FT COILED 168..250
FT /evidence="ECO:0000255"
SQ SEQUENCE 250 AA; 28797 MW; 528CB77FED80907F CRC64;
MEELDITSVG QFQTLVRYNN PVLVVKHPDK KGGAPLTEIE MKRPQTAGAL LDTKRETEEI
LNSILPPRCW EEDGQLWQQS VSSTPATRQD VINLQEMLDT RLQQTQARET GICPVRRELY
SQCFDEIIRQ VTINCSERGL LLLRIRDEIA MSMEAYETLY CSSVAFGMRK ALQAHEEKEM
LRDRVKTLEL DKEALEEIIA DMKLKQEQAE RRNAELRASE EKKFTEEITF LKKTNAQLKA
QLEGITAPKK
