ID   IE63_EHV2               Reviewed;         643 AA.
AC   Q66659;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-NOV-2015, sequence version 2.
DT   02-JUN-2021, entry version 64.
DE   RecName: Full=Immediate-early phosphoprotein 57;
GN   Name=57;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   Davison A.J.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL69 family. {ECO:0000305}.
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DR   EMBL; U20824; AAC13845.2; -; Genomic_DNA.
DR   PIR; S55652; S55652.
DR   RefSeq; NP_042654.2; NC_001650.2.
DR   SMR; Q66659; -.
DR   GeneID; 1461037; -.
DR   KEGG; vg:1461037; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR008648; ICP27-like.
DR   Pfam; PF05459; Herpes_UL69; 1.
PE   3: Inferred from homology;
KW   Early protein; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..643
FT                   /note="Immediate-early phosphoprotein 57"
FT                   /id="PRO_0000406032"
FT   REGION          1..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          194..329
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..52
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..102
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..152
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..320
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   643 AA;  71028 MW;  B7320D044F51B82A CRC64;
     MAQKMLEDQD MLDQLLSGVH DSDLDFSESE EEEEEEESSS ESESDEDSDM EVEPARQEAG
     PPEQCQQQPQ QRAREQQPPP QQQQPQQREQ GPPQQQQQQR TPKRGEESGD ARPRARAPSG
     DAGPGPSGQA RLPQQQQPQQ PQQPPPKPPR QEVTVRAPGD RQQPQSQAAQ PIPVIGGGCA
     PFQLRAPIAA AAATGWGGEQ APAQPLFQHV SPLNRRGDED RRSGRDRRRR EGRERDRESR
     SKGRNWYRPY PRGSSGARRE GGGRDAGQGQ GTRNPGPSQG GCEAGPSQAQ AAQAARAPRQ
     EQGERRQMLP QGQNLGPRPQ QCPPQQCPPQ PCPPFPLEAL PILRAKFEPS CAVSYTNLVK
     SIQKIAMPPF LMRRREASPP CHFSKIPQAT PGLVIPAAAR TGEAKFEKFT DAFVQKVIDR
     GMSPQDCINK TVSLRKLDAK FDPLKTFTAK TVNFGQWLDV RKDSIINSGM STQVVFLEEL
     CAWAKLNLQH GCNLEERDLI LHTAETVCSQ LMYKLKPIMS CLEPNKPYAS MAKQMAYLVC
     GAGRIQDAGM LLREVKVGSP LTMLVAFSLC VPVMITCRNR NPSLFNYCKS FLDMYQPGLL
     CALFNTMTSK LNTTCTEEEC YASVRAAIGS VVNTRGLLFV PGI