ID   IEND1_USTMA             Reviewed;         268 AA.
AC   Q0H8Z3;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Probable intron-encoded DNA endonuclease 1;
DE            EC=3.1.-.-;
GN   Name=hegI1; Synonyms=rnl;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OG   Mitochondrion.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RA   Kennell J.C., Boehmer C.;
RT   "Annotation of mitochondrial genome of Ustilago maydis and comparative
RT   analysis of basidiomycete mtDNAs.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
CC   -!- FUNCTION: Mitochondrial DNA endonuclease involved in intron homing.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion.
CC   -!- MISCELLANEOUS: Encoded within intron 1 (LRI1) of mitochondrial large
CC       subunit ribosomal RNA.
CC   -!- SIMILARITY: Belongs to the LAGLIDADG endonuclease family.
CC       {ECO:0000305}.
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DR   EMBL; DQ157700; AAZ67020.1; -; Genomic_DNA.
DR   EMBL; AACP01000277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; YP_762679.1; NC_008368.1.
DR   AlphaFoldDB; Q0H8Z3; -.
DR   SMR; Q0H8Z3; -.
DR   GeneID; 4308286; -.
DR   InParanoid; Q0H8Z3; -.
DR   Proteomes; UP000000561; Mitochondrion.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006314; P:intron homing; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.28.10; -; 2.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   Pfam; PF00961; LAGLIDADG_1; 2.
DR   SUPFAM; SSF55608; SSF55608; 2.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Intron homing; Mitochondrion; Nuclease;
KW   Reference proteome.
FT   CHAIN           1..268
FT                   /note="Probable intron-encoded DNA endonuclease 1"
FT                   /id="PRO_0000271166"
SQ   SEQUENCE   268 AA;  31301 MW;  3D186E5D6F1E3058 CRC64;
     MKTRLFNFTK WWLTGFTQAD GGFVVNFDAR KQGNLPYYPR PSFVLTQNIR EEQMMIELHG
     VGKLYYSRNE INIVVRSQDD ITNVIIPHFD NYSLRGHKLS SYFLFKEVVL MMNNGKHLSP
     FLQILELCYF TNHTTRRTLD TKKAILDKIY NKFGFVQFEP IIESNLSKPN SNPINNDYMV
     GLVDGDGSFN FGFKSTRRRI VPNFTIVQGV EDRSVLEDVQ SYLDCGKVYD LQSQTSRYQV
     ENVTDLVEKV LPEFKENKFN TTKKDYTL