ID   IEND3_USTMA             Reviewed;         136 AA.
AC   Q0H8Z1;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Probable intron-encoded DNA endonuclease 3;
DE            EC=3.1.-.-;
GN   Name=hegI3; Synonyms=rnl;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OG   Mitochondrion.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RA   Kennell J.C., Boehmer C.;
RT   "Annotation of mitochondrial genome of Ustilago maydis and comparative
RT   analysis of basidiomycete mtDNAs.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
CC   -!- FUNCTION: Mitochondrial DNA endonuclease involved in intron homing.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion.
CC   -!- MISCELLANEOUS: Encoded within intron 3 (LRI3) of mitochondrial large
CC       subunit ribosomal RNA.
CC   -!- SIMILARITY: Belongs to the LAGLIDADG endonuclease family.
CC       {ECO:0000305}.
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DR   EMBL; DQ157700; AAZ67022.1; -; Genomic_DNA.
DR   EMBL; AACP01000278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; YP_762681.1; NC_008368.1.
DR   AlphaFoldDB; Q0H8Z1; -.
DR   SMR; Q0H8Z1; -.
DR   STRING; 237631.Q0H8Z1; -.
DR   GeneID; 4308286; -.
DR   InParanoid; Q0H8Z1; -.
DR   Proteomes; UP000000561; Mitochondrion.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006314; P:intron homing; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.28.10; -; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   Pfam; PF03161; LAGLIDADG_2; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Intron homing; Mitochondrion; Nuclease;
KW   Reference proteome.
FT   CHAIN           1..136
FT                   /note="Probable intron-encoded DNA endonuclease 3"
FT                   /id="PRO_0000271167"
SQ   SEQUENCE   136 AA;  15786 MW;  1CCA7312FBCAE6B9 CRC64;
     MDGEVKSYWF KTFSHKSFSV IWDLFYNTSN GVTKKTINSG TILNHLNEVG LAYWVMGDGS
     LHREGRVLTL HTQGFSHDEN KMMSEELNLK FGFKSKVVKH KNKFVVQFTT SDANKLHDLI
     KPYLIPTMQY KLPRKL