ID   IER1_SOLLC              Reviewed;         119 AA.
AC   P20076;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Ethylene-responsive proteinase inhibitor 1;
DE   AltName: Full=Ethylene-responsive proteinase inhibitor I;
DE   Flags: Precursor;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2903499; DOI=10.1073/pnas.85.21.8012;
RA   Margossian L.J., Federman A.D., Giovannoni J.J., Fischer R.L.;
RT   "Ethylene-regulated expression of a tomato fruit ripening gene encoding a
RT   proteinase inhibitor I with a glutamic residue at the reactive site.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:8012-8016(1988).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I13 (potato type I serine
CC       protease inhibitor) family. {ECO:0000305}.
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DR   EMBL; J04099; AAA60745.1; -; mRNA.
DR   PIR; A32067; A32067.
DR   RefSeq; NP_001234615.1; NM_001247686.2.
DR   AlphaFoldDB; P20076; -.
DR   SMR; P20076; -.
DR   STRING; 4081.Solyc08g080630.2.1; -.
DR   PaxDb; P20076; -.
DR   PRIDE; P20076; -.
DR   GeneID; 543953; -.
DR   KEGG; sly:543953; -.
DR   eggNOG; ENOG502R80H; Eukaryota.
DR   HOGENOM; CLU_158942_4_1_1; -.
DR   InParanoid; P20076; -.
DR   OrthoDB; 1582946at2759; -.
DR   PhylomeDB; P20076; -.
DR   Proteomes; UP000004994; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009611; P:response to wounding; IEA:InterPro.
DR   InterPro; IPR000864; Prot_inh_pot1.
DR   InterPro; IPR036354; Prot_inh_pot1_sf.
DR   PANTHER; PTHR33091; PTHR33091; 1.
DR   Pfam; PF00280; potato_inhibit; 1.
DR   PRINTS; PR00292; POTATOINHBTR.
DR   SUPFAM; SSF54654; SSF54654; 1.
DR   PROSITE; PS00285; POTATO_INHIBITOR; 1.
PE   3: Inferred from homology;
KW   Protease inhibitor; Reference proteome; Secreted;
KW   Serine protease inhibitor; Signal.
FT   SIGNAL          1..27
FT   PROPEP          28..48
FT                   /id="PRO_0000025302"
FT   CHAIN           49..119
FT                   /note="Ethylene-responsive proteinase inhibitor 1"
FT                   /id="PRO_0000025303"
FT   SITE            95..96
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   119 AA;  13160 MW;  669D30211FA65DA9 CRC64;
     MEANKSMVKL VAFLIILVSS CFQSLTAQDL EIEVSDGLNV LQVHDVSQSF CPGVTKESWP
     ELLGTPAKFA KQIIQKENPK LTNVETLLNG SAFTEDLRCN RVRLFVNLLD IVVQTPKVG