IER5L_DANRE
ID IER5L_DANRE Reviewed; 301 AA.
AC Q6NYT3; Q6PBN7;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 2.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Immediate early response gene 5-like protein;
GN Name=ier5l; ORFNames=si:ch211-208h16.10, zgc:77455;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo, and Eye;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IER family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH59641.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAH66470.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAM13727.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CR925757; CAM13727.1; ALT_INIT; Genomic_DNA.
DR EMBL; BC059641; AAH59641.1; ALT_INIT; mRNA.
DR EMBL; BC066470; AAH66470.1; ALT_INIT; mRNA.
DR RefSeq; NP_956048.1; NM_199754.1.
DR AlphaFoldDB; Q6NYT3; -.
DR STRING; 7955.ENSDARP00000071657; -.
DR PaxDb; Q6NYT3; -.
DR Ensembl; ENSDART00000180452; ENSDARP00000153430; ENSDARG00000114072.
DR Ensembl; ENSDART00000186789; ENSDARP00000150165; ENSDARG00000110793.
DR GeneID; 326935; -.
DR KEGG; dre:326935; -.
DR CTD; 389792; -.
DR ZFIN; ZDB-GENE-030131-5134; ier5l.
DR eggNOG; ENOG502QUU4; Eukaryota.
DR InParanoid; Q6NYT3; -.
DR OrthoDB; 928914at2759; -.
DR PhylomeDB; Q6NYT3; -.
DR TreeFam; TF331376; -.
DR PRO; PR:Q6NYT3; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR Bgee; ENSDARG00000114072; Expressed in midbrain neural keel and 6 other tissues.
DR InterPro; IPR008653; IER.
DR PANTHER; PTHR15895; PTHR15895; 2.
DR Pfam; PF05760; IER; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..301
FT /note="Immediate early response gene 5-like protein"
FT /id="PRO_0000334659"
FT CONFLICT 85
FT /note="D -> E (in Ref. 2; AAH66470)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 301 AA; 32938 MW; D9988225BCBE6CB4 CRC64;
MECAVDAQSL ISISLRKIHN SRTQRGGIKL HKNLLVSYVL RNARQVYMNE KYAEIYRMQQ
YEEVMTVCNE IQELNPLDLA EDCEDQTADC CGSASESASL CGALLPAVGH QTSPAAQHIQ
PASACSVPLA LQSEEVCKAA PEPSFYRSCC AEAYPVSNCD FSPVNNMHCN KTTVLDLDTH
VVTTVENGYL HQDCCASLQQ CCQGAQSPAK KRKLDFGYYV SEIEEAPDFT PCKRAKFEDS
SYAITEPLDT SNISNLISIF GSGFSGLVSR QADLEQALNG QFCSKQALAS LGAWTRAIVA
F