IES1_EMENI
ID IES1_EMENI Reviewed; 780 AA.
AC C8V8H5; P0C2M6; Q5B4R4;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 1.
DT 03-AUG-2022, entry version 47.
DE RecName: Full=Ino eighty subunit 1;
GN ORFNames=AN10560;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Probably involved in transcription regulation via its
CC interaction with the INO80 complex, a chromatin-remodeling complex.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the chromatin-remodeling INO80 complex.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA60231.1; Type=Erroneous gene model prediction; Note=The predicted gene AN4466 has been split into 2 genes: AN10557 and AN10560.; Evidence={ECO:0000305};
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DR EMBL; AACD01000077; EAA60231.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BN001303; CBF77463.1; -; Genomic_DNA.
DR RefSeq; XP_662070.1; XM_656978.1.
DR AlphaFoldDB; C8V8H5; -.
DR STRING; 162425.CADANIAP00005986; -.
DR EnsemblFungi; CBF77463; CBF77463; ANIA_10560.
DR EnsemblFungi; EAA60231; EAA60231; AN4466.2.
DR GeneID; 2872265; -.
DR KEGG; ani:AN4466.2; -.
DR eggNOG; ENOG502QVDM; Eukaryota.
DR HOGENOM; CLU_003735_0_0_1; -.
DR InParanoid; C8V8H5; -.
DR OMA; IAELHFP; -.
DR OrthoDB; 786944at2759; -.
DR Proteomes; UP000000560; Chromosome III.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0031011; C:Ino80 complex; IBA:GO_Central.
DR InterPro; IPR038014; Ies1.
DR PANTHER; PTHR37287; PTHR37287; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..780
FT /note="Ino eighty subunit 1"
FT /id="PRO_0000413171"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..693
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..750
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 780 AA; 87755 MW; EF3D6B419EB1A23F CRC64;
MADVESAGVD DSFAQSEPHD EQQIHNMTVG TRRQPNGTIG SVYSGNKIRH LKKEDGIPLW
RKDIQYQFLK LVFEDKTPVF TRWPDGQKNM DFADIYIDAM ARSSKTSKIL KDKLQSDKQA
AINMAMVCLL VNFGRMNTTL NFFPEMRAQL RTYHSIPSLQ AHQDPNAYKQ LQDAPRLKSI
LKGASEDVDQ PNTLDKIKRE NVPRTNPVNL IFVLAQYAPK VSEMHFFPPR DFFDLVMRST
LSSKSRAKAF LWLMWWYLES DFSREAALNN PFGPGLEGEG TGGLPIKVPS FEILTEEQAN
EENVDTQSEI EYGEEKRLER KRILEEEEPT PRAPKRPKKM PYWEFQYLKQ MEPGTKIPSR
QFSNKGDAYR AAADSDDLIE FRNPDGSIRS TLKMPRDEDY AYQSGSLDGP SPRIVLRTKA
ENTPDAASPA PPGSGYPILN RFVTEASPHH QGSSRRPRPL TQHQLAVERN RRQRIEYILA
KRKGEAYRLL RAKRLTEIPF ARYGRLLQNL PDGYDTDDDK SWGKGGLLPN PEEEEDFGEC
ANYFLSVIRK ASRRLDRWDY EHANGPRRDR KKEREERQKA REEAMDFDGD VDGKVSSRSS
RARAQRNAKR KLARAAAAAS STPSASTPKT AAARSKGNRS RNPRDEKVAA ATSLGANTGL
ETPSRDDALS PVQGDLEGEE SLDDIDRELL GEGSGDEDDI PPRGLEPSRP AELGYDDSFL
GGDADDALSS DEEEEEAEDE ELDEMDVEGD DNLSAPGGEG RYAASDVSGP EMANGKPGWN
