IES6_SCHPO
ID IES6_SCHPO Reviewed; 117 AA.
AC Q9UTE8;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Chromatin-remodeling complex subunit ies6;
GN Name=ies6; ORFNames=SPAC222.04c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Probably involved in transcription regulation via its
CC interaction with the INO80 complex, a chromatin remodeling complex.
CC Also involved in the regulation of telomere length (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the chromatin-remodeling INO80 complex.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IES6 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB60696.1; -; Genomic_DNA.
DR PIR; T50145; T50145.
DR RefSeq; NP_593143.1; NM_001018540.2.
DR AlphaFoldDB; Q9UTE8; -.
DR SMR; Q9UTE8; -.
DR BioGRID; 278436; 5.
DR STRING; 4896.SPAC222.04c.1; -.
DR MaxQB; Q9UTE8; -.
DR PaxDb; Q9UTE8; -.
DR EnsemblFungi; SPAC222.04c.1; SPAC222.04c.1:pep; SPAC222.04c.
DR GeneID; 2541949; -.
DR KEGG; spo:SPAC222.04c; -.
DR PomBase; SPAC222.04c; ies6.
DR VEuPathDB; FungiDB:SPAC222.04c; -.
DR eggNOG; KOG4137; Eukaryota.
DR HOGENOM; CLU_071116_2_1_1; -.
DR InParanoid; Q9UTE8; -.
DR OMA; HNVEIYQ; -.
DR PhylomeDB; Q9UTE8; -.
DR PRO; PR:Q9UTE8; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0000785; C:chromatin; IDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0031011; C:Ino80 complex; IDA:PomBase.
DR GO; GO:0034080; P:CENP-A containing chromatin assembly; IMP:PomBase.
DR GO; GO:0006338; P:chromatin remodeling; IDA:PomBase.
DR GO; GO:0071931; P:positive regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:PomBase.
DR InterPro; IPR029525; INO80C/Ies6.
DR InterPro; IPR013272; Vps72/YL1_C.
DR PANTHER; PTHR31200; PTHR31200; 1.
DR Pfam; PF08265; YL1_C; 1.
DR SMART; SM00993; YL1_C; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..117
FT /note="Chromatin-remodeling complex subunit ies6"
FT /id="PRO_0000339139"
SQ SEQUENCE 117 AA; 13476 MW; 3EF1C931D176A529 CRC64;
MEKNSSVDSL DISLLARPFR NPNYKAQPRR NRNLRQIIQN DPVQNEPSKF SYSSIEAPPS
VLPQPKYCDV TGLLAIYTDP KTRLRYHNKE IYGLIRELPS GADQEYLKLR SSDVVLK