ID   IF1A1_HALSA             Reviewed;          95 AA.
AC   Q9HN64;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Translation initiation factor 1A 1;
DE            Short=aIF-1A 1;
GN   Name=eIF1A1; OrderedLocusNames=VNG_2234G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: Seems to be required for maximal rate of protein
CC       biosynthesis. Enhances ribosome dissociation into subunits and
CC       stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal
CC       subunits (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eIF-1A family. {ECO:0000305}.
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DR   EMBL; AE004437; AAG20357.1; -; Genomic_DNA.
DR   PIR; A84374; A84374.
DR   RefSeq; WP_010903658.1; NC_002607.1.
DR   AlphaFoldDB; Q9HN64; -.
DR   SMR; Q9HN64; -.
DR   STRING; 64091.VNG_2234G; -.
DR   PaxDb; Q9HN64; -.
DR   EnsemblBacteria; AAG20357; AAG20357; VNG_2234G.
DR   GeneID; 5953299; -.
DR   GeneID; 62887518; -.
DR   KEGG; hal:VNG_2234G; -.
DR   PATRIC; fig|64091.14.peg.1717; -.
DR   HOGENOM; CLU_109098_1_2_2; -.
DR   InParanoid; Q9HN64; -.
DR   OMA; ADITWRY; -.
DR   OrthoDB; 102432at2157; -.
DR   PhylomeDB; Q9HN64; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR   CDD; cd05793; S1_IF1A; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00216; aIF_1A; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   InterPro; IPR018104; TIF_eIF-1A_CS.
DR   PANTHER; PTHR21668; PTHR21668; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00523; eIF-1A; 1.
DR   PROSITE; PS01262; IF1A; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..95
FT                   /note="Translation initiation factor 1A 1"
FT                   /id="PRO_0000145116"
FT   DOMAIN          7..81
FT                   /note="S1-like"
SQ   SEQUENCE   95 AA;  11148 MW;  831A389F30708686 CRC64;
     MSDDGGGRKN LRMPEDDEVF AEVTDMLGAN RVQVRCADGE ERTARIPGRM QKRIWIREDD
     IVLVEPWDWQ DDKADVTWRY EKSDADQLRE EGHIE