ID   IF1A2_HALSA             Reviewed;          94 AA.
AC   Q9HP87;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Translation initiation factor 1A 2;
DE            Short=aIF-1A 2;
GN   Name=eIF1A2; OrderedLocusNames=VNG_1756G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: Seems to be required for maximal rate of protein
CC       biosynthesis. Enhances ribosome dissociation into subunits and
CC       stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal
CC       subunits (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eIF-1A family. {ECO:0000305}.
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DR   EMBL; AE004437; AAG19983.1; -; Genomic_DNA.
DR   PIR; C84327; C84327.
DR   RefSeq; WP_049892515.1; NC_002607.1.
DR   AlphaFoldDB; Q9HP87; -.
DR   SMR; Q9HP87; -.
DR   STRING; 64091.VNG_1756G; -.
DR   PaxDb; Q9HP87; -.
DR   EnsemblBacteria; AAG19983; AAG19983; VNG_1756G.
DR   GeneID; 5953670; -.
DR   GeneID; 62887137; -.
DR   KEGG; hal:VNG_1756G; -.
DR   PATRIC; fig|64091.14.peg.1338; -.
DR   HOGENOM; CLU_109098_1_2_2; -.
DR   InParanoid; Q9HP87; -.
DR   OrthoDB; 102432at2157; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR   CDD; cd05793; S1_IF1A; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00216; aIF_1A; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   InterPro; IPR018104; TIF_eIF-1A_CS.
DR   PANTHER; PTHR21668; PTHR21668; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS01262; IF1A; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..94
FT                   /note="Translation initiation factor 1A 2"
FT                   /id="PRO_0000145117"
FT   DOMAIN          6..80
FT                   /note="S1-like"
SQ   SEQUENCE   94 AA;  11101 MW;  04B775E2B1F7328D CRC64;
     MSDESGRRNL RMPNDDEVFA VVKRHDGGNH VTLQCEDGKE RMGRIPGRMK YRTWINEGDV
     VLAEPWDWQD EKANVEWRYS DQDADQLREE GHIE